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Trains from Lyon to Brussels Midi

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  3. Lyon to Brussels Midi

About the train journey from Lyon to Brussels Midi

Want to travel from Lyon to Brussels Midi by train? Start your journey with us.

The train from Lyon to Brussels Midi usually takes 4 hours 50 minutes on average to travel 351 miles (565 km), although the quickest services can take as little as 3 hours 43 minutes. You can expect to find 29 trains per day running on this popular route. Good news! There are direct trains available to Brussels Midi, so you can just make yourself comfortable as soon as you board the train and just enjoy the journey.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Lyon to Brussels Midi in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save, as advance tickets start from £40.11.

Keep reading for more information about the train journey to Brussels Midi, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Trains to Brussels Midi from Lyon

It takes an average of 4h 50m to travel from Lyon to Brussels Midi by train, over a distance of around 351 miles (565 km). There are normally 29 trains per day travelling from Lyon to Brussels Midi and tickets for this journey start from £40.11 when you book in advance.

First train

05:49

Last train

21:04

Departure stationLyon
Arrival stationBrussels Midi
Journey time

From 3h 43m

Distance

351 miles (565 km)

Frequency

29 trains per day

Changes

Direct trains available

Price

From £40.11

Train and bus operators

BlaBlaCar Bus, Flixbus, SNCF Voyageurs

What do people frequently ask about the train journey from Lyon to Brussels Midi?

Want to know more about your journey from Lyon to Brussels Midi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Lyon to Brussels Midi?

You can get from Lyon to Brussels Midi by train in 4 hours and 50 minutes on average, with the fastest journeys taking just 3 hours and 43 minutes. You can also take the bus from Lyon to Brussels Midi. Check out our Journey Planner for more details.

How long does the train from Lyon to Brussels Midi take?

The average journey time by train between Lyon and Brussels Midi is 4 hours and 50 minutes, with around 29 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

How much does the train from Lyon to Brussels Midi cost?

Train tickets from Lyon to Brussels Midi can start from as little as £40.11 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending on the time of day, route and class you book.

What's the fastest journey time between Lyon and Brussels Midi by train?

The fastest journey time by train from Lyon to Brussels Midi is 3 hours and 43 minutes.

What are the train times from Lyon to Brussels Midi?

Check out the next trains departing from Lyon to Brussels Midi for Tuesday 13th January 2026. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:5012:444h 54m, 1 change
08:0413:055h 1m, 1 change
09:0413:174h 13m, 1 change
10:0014:264h 26m, direct
10:0414:444h 40m, 1 change
10:3414:444h 10m, 1 change
12:0416:174h 13m, 1 change
13:0016:433h 43m, direct
13:0417:474h 43m, 1 change
13:3017:474h 17m, 1 change

How do I find cheap train tickets from Lyon to Brussels Midi?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Lyon to Brussels Midi starts at £40.11§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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