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Trains from Brussels Midi to Lyon

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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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  3. Brussels Midi to Lyon

About the train journey from Brussels Midi to Lyon

Want to travel from Brussels Midi to Lyon by train? Start your journey with us.

The train from Brussels Midi to Lyon usually takes 4 hours 35 minutes on average to travel 351 miles (565 km), although the quickest services can take as little as 3 hours 43 minutes. You can expect to find 32 trains per day running on this popular route. Good news! There are direct trains available to Lyon, so you can just make yourself comfortable as soon as you board the train and just enjoy the journey.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Brussels Midi to Lyon in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save, as advance tickets start from £47.41.

Keep reading for more information about the train journey to Lyon, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Trains to Lyon from Brussels Midi

It takes an average of 4h 35m to travel from Brussels Midi to Lyon by train, over a distance of around 351 miles (565 km). There are normally 32 trains per day travelling from Brussels Midi to Lyon and tickets for this journey start from £47.41 when you book in advance.

First train

06:27

Last train

21:16

Departure stationBrussels Midi
Arrival stationLyon
Journey time

From 3h 43m

Distance

351 miles (565 km)

Frequency

32 trains per day

Changes

Direct trains available

Price

From £47.41

Train and bus operators

BlaBlaCar Bus, Flixbus, SNCF Voyageurs

What do people frequently ask about the train journey from Brussels Midi to Lyon?

Want to know more about your journey from Brussels Midi to Lyon? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Brussels Midi to Lyon?

You can get from Brussels Midi to Lyon by train in 4 hours and 35 minutes on average, with the fastest journeys taking just 3 hours and 43 minutes. You can also take the bus from Brussels Midi to Lyon. Check out our Journey Planner for more details.

How long does the train from Brussels Midi to Lyon take?

The average journey time by train between Brussels Midi and Lyon is 4 hours and 35 minutes, with around 32 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

How much does the train from Brussels Midi to Lyon cost?

Train tickets from Brussels Midi to Lyon can start from as little as £47.41 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending on the time of day, route and class you book.

What's the fastest journey time between Brussels Midi and Lyon by train?

The fastest journey time by train from Brussels Midi to Lyon is 3 hours and 43 minutes.

What are the train times from Brussels Midi to Lyon?

Check out the next trains departing from Brussels Midi to Lyon for Tuesday 13th January 2026. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
09:1713:003h 43m, direct
09:4213:564h 14m, 1 change
10:1314:564h 43m, 1 change
10:1415:565h 42m, 3 changes
12:0715:593h 52m, direct
12:1316:184h 5m, 1 change
12:1317:004h 47m, 1 change
13:4317:564h 13m, 1 change
13:4318:224h 39m, 1 change
14:1618:224h 6m, 1 change

How do I find cheap train tickets from Brussels Midi to Lyon?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Brussels Midi to Lyon starts at £47.41§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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