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Trains from Lyon Perrache to Brussels Midi

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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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  3. Lyon Perrache to Brussels Midi

Travel from Lyon Perrache to Brussels Midi by train in 4 hours 1 minute

If you want to know more about the journey from Lyon Perrache to Brussels Midi by train, look no further!

The average journey time from Lyon Perrache to Brussels Midi by train is 5 hours 23 minutes, although on the fastest services it can take just 4 hours 1 minute. Around 29 trains per day travel the 352 miles (567 km) between these two destinations. Direct trains are usually available every day on the route to Brussels Midi.

Book train tickets from Lyon Perrache to Brussels Midi in advance instead of buying them on the day and they can start from £63.62. We'll always highlight the cheapest prices when you search in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Trains to Brussels Midi from Lyon Perrache

It takes an average of 5h 23m to travel from Lyon Perrache to Brussels Midi by train, over a distance of around 352 miles (567 km). There are normally 29 trains per day travelling from Lyon Perrache to Brussels Midi and tickets for this journey start from £63.62 when you book in advance.

First train

05:35

Last train

20:50

Departure stationLyon Perrache
Arrival stationBrussels Midi
Journey time

From 4h 1m

Distance

352 miles (567 km)

Frequency

29 trains per day

Changes

Direct trains available

Price

From £63.62

Train and bus operators

BlaBlaCar Bus, Flixbus, SNCF Voyageurs

What do people frequently ask about the train journey from Lyon Perrache to Brussels Midi?

Want to know more about your journey from Lyon Perrache to Brussels Midi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Lyon Perrache to Brussels Midi?

You can travel from Lyon Perrache to Brussels Midi by train in about 5 hours and 23 minutes. With around 29 trains running each day, taking the train is easy. If you’re looking for other options, you can also catch the bus from Lyon Perrache to Brussels Midi. Find out more in our Journey Planner.

How long is the train journey from Lyon Perrache to Brussels Midi?

On average, the train journey from Lyon Perrache to Brussels Midi takes around 5 hours and 23 minutes, with 29 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

How much is the train from Lyon Perrache to Brussels Midi?

Train tickets from Lyon Perrache to Brussels Midi start from as little as £63.62, depending on the time of booking, class of service and type of train. Booking in advance often results in cheaper prices.

What is the fastest train from Lyon Perrache to Brussels Midi?

The fastest trains from Lyon Perrache to Brussels Midi can cover the distance of 352 miles (567 km) in as little as 4 hours and 1 minute.

What are the train times from Lyon Perrache to Brussels Midi?

Check out the next trains departing from Lyon Perrache to Brussels Midi for Tuesday 23rd December 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
08:5013:174h 27m, 1 change
09:1614:265h 10m, 1 change
09:5014:444h 54m, 1 change
10:1614:444h 28m, 1 change
11:4416:174h 33m, 1 change
12:3816:434h 5m, 1 change
12:5017:474h 57m, 1 change
13:1617:474h 31m, 1 change
13:1618:175h 1m, 1 change
13:5018:174h 27m, 1 change

How do I find cheap train tickets from Lyon Perrache to Brussels Midi?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Lyon Perrache to Brussels Midi starts at £63.62§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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