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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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How to travel from Palermo to Milan Central Station by train

Want to find out more about taking the train from Palermo to Milan Central Station? Look no further.

There are around 12 trains per day running between Palermo and Milan Central Station, which usually take 17 hours 28 minutes to complete the 552 miles (888 km) journey. It can take as little as 12 hours 33 minutes on the fastest services though, if you want to get there as quickly as possible. As soon as you board the train, you'll be able to make yourself comfortable and enjoy the journey as there are direct services available. All or part of your journey will be on board a Trenitalia train, as they are the main operator of trains on this route.

You can save money on train tickets from Palermo to Milan Central Station if you book in advance, as tickets usually start from £68.03. Use our Journey Planner at the top of the page to compare ticket prices and get the cheapest fares.

Want to book your train tickets now? Just start a search with us today. If you want to find out more about the journey, read on for timetables (including first and last train times), FAQs and tips on how to book cheap train tickets.

Trains to Milan Central Station from Palermo

It takes an average of 17h 28m to travel from Palermo to Milan Central Station by train, over a distance of around 552 miles (888 km). There are normally 12 trains per day travelling from Palermo to Milan Central Station and tickets for this journey start from £68.03 when you book in advance.

First train

06:19

Last train

21:35

Departure stationPalermo
Arrival stationMilan Central Station
Journey time

From 12h 33m

Distance

552 miles (888 km)

Frequency

12 trains per day

Changes

Direct trains available

Price

From £68.03

Train and bus operators

Autoservizi Salemi, Flixbus, Trenitalia

What do people frequently ask about the train journey from Palermo to Milan Central Station?

Want to know more about your journey from Palermo to Milan Central Station? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Palermo to Milan Central Station?

You can travel from Palermo to Milan Central Station by train in about 17 hours and 28 minutes. With around 12 trains running each day, taking the train is easy. Find out more in our Journey Planner.

How long is the train journey from Palermo to Milan Central Station?

On average, the train journey from Palermo to Milan Central Station takes around 17 hours and 28 minutes, with 12 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

How much is the train from Palermo to Milan Central Station?

Train tickets from Palermo to Milan Central Station start from as little as £68.03, depending on the time of booking, class of service and type of train. Booking in advance often results in cheaper prices.

What is the fastest train from Palermo to Milan Central Station?

The fastest trains from Palermo to Milan Central Station can cover the distance of 552 miles (888 km) in as little as 12 hours and 33 minutes.

What are the train times from Palermo to Milan Central Station?

Check out the next trains departing from Palermo to Milan Central Station for Tuesday 20th January 2026. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
05:1918:5013h 31m, 2 changes
06:0520:0013h 55m, 1 change
07:2720:0012h 33m, 2 changes
09:1505:5520h 40m, 1 change
09:1507:3022h 15m, 1 change
11:5507:3019h 35m, 3 changes
11:5507:5019h 55m, 1 change
11:5509:1021h 15m, direct
17:5309:5816h 5m, 1 change
19:2511:5816h 33m, 1 change

Trenitalia trains from Palermo to Milan Central Station

You can travel from Palermo to Milan Central Station on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

What Intercity Notte (night trains) classes are there from Palermo to Milan Central Station?

Compare the different travel classes offered by Intercity Notte (night trains) when travelling from Palermo to Milan Central Station.

What are the onboard services on Intercity Notte (night trains)?

Discover more about the onboard services offered on trains from Palermo to Milan Central Station.

LuggageLuggageWhat luggage limits are there?
  • You can take your bags on board Trenitalia's Intercity Notte trains free of charge.
  • In most cases, there are no luggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your luggage is compatible with the space available on board.
RestaurantRestaurantWhat food and drink is available?

A minibar trolley service is available on all Intercity Notte trains – you can choose from a wide range of snacks and drinks. Vegan, gluten-free and lactose-free options are available too.

WiFiWiFiWhat onboard entertainment is available?

Unfortunately, free WiFi is not available on Intercity Notte trains.

ChildPassengerChildPassengerWhat facilities are there for travel with children?
  • Children under 4 can travel for free if a seat is not assigned to them. If they do have a seat, they can get 50% off Base tickets (standard fare).
  • Children aged 4-14 also get 50% off, or 30% off if they’re travelling in the Comfort couchette or Deluxe cabin Relax.
ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?
  • You can take your folding bike with you if it’s stored in one of the dedicated luggage spaces.
  • If you have a traditional bike, you’ll need to disassemble it and place it in a bag that is not larger than 80 x 110 x 45cm.
PetPetCan I bring pets on board?
  • Small pets are allowed on board free of charge, if they’re placed in a carrier or cage of max dimensions of 70 x 30 x 50cm. You’ll need to buy a ticket for the whole compartment.
  • Bigger dogs are allowed on board if they have a ticket – it’s usually 50% off the Base ticket (standard fare).
WheelchairWheelchairWhat special assistance is available?

Intercity Notte trains have a coach with designated spaces for 2 passengers with a wheelchair and 2 companions. You’ll find a wheelchair symbol outside the coach.

InfoInfoWhat else do I need to know?

Depending on the class you’ll be travelling in, you’ll get to enjoy additional perks, including a wake-up service, breakfast, bedding and more.

How do I find cheap train tickets from Palermo to Milan Central Station?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Palermo to Milan Central Station starts at £68.03§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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