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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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About the train journey from Palermo Centrale to Siena

Want to travel from Palermo Centrale to Siena by train? Start your journey with us.

The train from Palermo Centrale to Siena usually takes 16 hours 26 minutes on average to travel 376 miles (606 km), although the quickest services can take as little as 13 hours 16 minutes. You can expect to find 17 trains per day running on this popular route. As there aren’t any direct services running between Palermo Centrale and Siena, you’ll need to make 1 change on your way to Siena.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Palermo Centrale to Siena in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save, as advance tickets start from £64.23.

Keep reading for more information about the train journey to Siena, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Palermo Centrale to Siena by train

It takes an average of 16h 26m to travel from Palermo Centrale to Siena by train, over a distance of around 376 miles (606 km). There are normally 17 trains per day travelling from Palermo Centrale to Siena and tickets for this journey start from £64.23 when you book in advance.

First train

05:07

Last train

20:25

Departure station

Palermo Centrale

Arrival station

Siena

Journey time

From 13h 16m

Distance

376 miles (606 km)

Frequency

17 trains per day

Changes

1 change

Price

From £64.23

Train and bus operators

Flixbus

FAQs about the train journey from Palermo Centrale to Siena

Want to know more about your journey from Palermo Centrale to Siena? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Palermo Centrale to Siena?

You can travel from Palermo Centrale to Siena by train in about 16 hours and 26 minutes. With around 17 trains running each day, taking the train is easy. Find out more in our Journey Planner.

How long is the train journey from Palermo Centrale to Siena?

On average, the train journey from Palermo Centrale to Siena takes around 16 hours and 26 minutes, with 17 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

How much is the train from Palermo Centrale to Siena?

Train tickets from Palermo Centrale to Siena start from as little as £64.23, depending on the time of booking, class of service and type of train. Booking in advance often results in cheaper prices.

What is the fastest train from Palermo Centrale to Siena?

The fastest trains from Palermo Centrale to Siena can cover the distance of 376 miles (606 km) in as little as 13 hours and 16 minutes.

Palermo Centrale to Siena train times

Check out the next trains departing from Palermo Centrale to Siena for Tuesday 6th May 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
06:0520:1614h 11m, 4 changes
06:0520:2514h 20m, 3 changes
07:1320:3913h 26m, 4 changes
09:1504:4919h 34m, 2 changes
09:1504:4919h 34m, 3 changes
11:5806:5518h 57m, 1 change
11:5806:5518h 57m, 3 changes
16:2009:1616h 56m, 3 changes
16:2009:4017h 20m, 2 changes
16:2008:3816h 18m, 4 changes

Cheap train tickets from Palermo Centrale to Siena

The price of train tickets from Palermo Centrale to Siena starts at £64.23 one-way for a Standard Class ticket if you book in advance. Booking on the day is usually more expensive and costs can vary depending on the time of day, route or class.

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Palermo Centrale to Siena by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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