Want stress-free journeys? Now you can plan around disruptions, rebook and get help with Delay Repay. Find out more

Skip to contentTrainline homepage
RailcardsBusiness

No tickets in your basket.

Why not plan a trip?

My Bookings
Loading...
Loading...

Trains from Siena to Palermo

Booking.com

ExternalLinkExternalLink

Open Booking.com in a new tab with places to stay on your trip

Trenitalia
Italo

Compare prices from over 270 rail and coach companies in Europe

Icon of trainline-phone-tickets.svg

Buy your tickets with us and easily find them on your phone

Icon of trainline-safe-payments.svg

Safely pay with PayPal, Visa and all international payment cards

What customers say about Trainline

Read real reviews from real users

Trustpilot
  1. Home
  2. Train times
  3. Siena to Palermo

Travel from Siena to Palermo by train in 14 hours 13 minutes

If you want to know more about the journey from Siena to Palermo by train, look no further!

The average journey time from Siena to Palermo by train is 17 hours 43 minutes, although on the fastest services it can take just 14 hours 13 minutes. Around 10 trains per day travel the 375 miles (604 km) between these two destinations. You'll need to make 1 change along the way to Palermo.

Book train tickets from Siena to Palermo in advance instead of buying them on the day and you'll snap up the cheapest fares. You can check prices from Siena to Palermo in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Trains to Palermo from Siena

First train

08:18

Last train

21:40

Departure stationSiena
Arrival stationPalermo
Journey time

From 14h 13m

Distance

375 miles (604 km)

Frequency

10 trains per day

Changes

1 change

Train and bus operators

Flixbus

What do people frequently ask about the train journey from Siena to Palermo?

Want to know more about your journey from Siena to Palermo? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Siena to Palermo?

You can get from Siena to Palermo by train in 17 hours and 43 minutes on average, with the fastest journeys taking just 14 hours and 13 minutes. Check out our Journey Planner for more details.

How long does the train from Siena to Palermo take?

The average journey time by train between Siena and Palermo is 17 hours and 43 minutes, with around 10 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

What's the fastest journey time between Siena and Palermo by train?

The fastest journey time by train from Siena to Palermo is 14 hours and 13 minutes.

Can you take a train directly from Siena to Palermo?

No, there are no direct train services from Siena to Palermo. Travelling from Siena to Palermo by train will require a minimum of 1 change.

What are the train times from Siena to Palermo?

Check out the next trains departing from Siena to Palermo for Tuesday 3rd March 2026. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:1822:0114h 43m, 2 changes
07:4822:0114h 13m, 3 changes
08:1805:2821h 10m, 6 changes
11:1806:4719h 29m, 3 changes
12:3206:4718h 15m, 4 changes
13:1806:4717h 29m, 5 changes
15:1808:1116h 53m, 2 changes
18:1812:1217h 54m, 2 changes
20:4014:2717h 47m, 3 changes
20:4015:5919h 19m, 1 change

How do I find cheap train tickets from Siena to Palermo?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Siena to Palermo starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

Looking for more ideas?

Europe’s leading train and coach app

We help customers across Europe make more than 172,000 smarter journeys every day.

Get a link