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Trains from Palermo Centrale to Milan Central Station

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  3. Palermo Centrale to Milan Central Station

Taking the train from Palermo Centrale to Milan Central Station in 12 hours 53 minutes

Thinking about taking the train from Palermo Centrale to Milan Central Station? We’ve got you covered.

It usually takes around 17 hours 19 minutes to travel the 553 miles (890 km) from Palermo Centrale to Milan Central Station by train, although you can get there in as little as 12 hours 53 minutes on the fastest services. You’ll normally find around 19 trains per day running on this route. You’ll need to make 1 change along the way as there aren't any direct services on this line. You can travel with Trenitalia trains during your journey, as they are the main operator of services on this route.

Train tickets from Palermo Centrale to Milan Central Station start from £60.28 when you book in advance, which can be cheaper than buying them on the day. Start a search in our Journey Planner to check out the latest prices.

Keen to book your train tickets to Milan Central Station? No need to wait, start a search with us today! If you want to find out a bit more about the journey first, you can find our train timetable below, tips on booking cheap tickets and our FAQs, including first and last train times.

Trains to Milan Central Station from Palermo Centrale

It takes an average of 17h 19m to travel from Palermo Centrale to Milan Central Station by train, over a distance of around 553 miles (890 km). There are normally 19 trains per day travelling from Palermo Centrale to Milan Central Station and tickets for this journey start from £60.28 when you book in advance.

First train

05:07

Last train

20:25

Departure stationPalermo Centrale
Arrival stationMilan Central Station
Journey time

From 12h 53m

Distance

553 miles (890 km)

Frequency

19 trains per day

Changes

1 change

Price

From £60.28

Train and bus operators

Autoservizi Salemi, Flixbus, Trenitalia

What do people frequently ask about the train journey from Palermo Centrale to Milan Central Station?

Want to know more about your journey from Palermo Centrale to Milan Central Station? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Milan Central Station from Palermo Centrale?

To get to Milan Central Station from Palermo Centrale, why not take the train? With 19 trains per day and an average journey time of 17 hours and 19 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Palermo Centrale to Milan Central Station by train?

On average, it takes around 17 hours and 19 minutes to travel from Palermo Centrale to Milan Central Station by train, although you can get there in 12 hours and 53 minutes on the fastest services. With 19 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Palermo Centrale to Milan Central Station?

The price of a train ticket from Palermo Centrale to Milan Central Station can start from as little as £60.28, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Palermo Centrale to Milan Central Station?

The fastest time a train can travel the 553 miles (890 km) from Palermo Centrale to Milan Central Station is 12 hours and 53 minutes.

What are the train times from Palermo Centrale to Milan Central Station?

Check out the next trains departing from Palermo Centrale to Milan Central Station for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:1322:0014h 47m, 3 changes
09:1506:0520h 50m, 2 changes
09:1507:3022h 15m, 1 change
09:1506:0520h 50m, 3 changes
09:1507:3022h 15m, 2 changes
11:5807:5019h 52m, 1 change
11:5807:5019h 52m, 3 changes
11:5809:0021h 2m, 2 changes
15:3209:0017h 28m, 3 changes
17:4809:5816h 10m, 1 change

Trenitalia trains from Palermo Centrale to Milan Central Station

You can travel from Palermo Centrale to Milan Central Station on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

More information

What Intercity Notte (night trains) classes are there from Palermo Centrale to Milan Central Station?

Compare the different travel classes offered by Intercity Notte (night trains) when travelling from Palermo Centrale to Milan Central Station.

Seated coach Basic Easy

If you're travelling on a budget, buy a ticket for a basic seat - you'll find a spacious and comfy seat with a fold-down table, as well as a minibar service.

  • SeatSeatFold-down table
  • BarBarMinibar
  • ReadingReadingReading light
  • LuggageLuggageLuggage storage
  • PlugPlugPower sockets
  • PlugPlugUSB sockets
  • OvernightOvernightBedding
  • CoffeeCoffeeBreakfast
  • BarBarBottle of water
  • WashbasinWashbasinToiletries
  • LegRoomLegRoomMore legroom
  • ReceiptReceiptFree magazines/newspapers
  • PlusPlusClothes hanger
  • Alarm clockAlarm clockWakeup service
  • WashbasinWashbasinPrivate bathroom
  • BarBarWelcome drink
  • ShowPasswordShowPasswordMirror

    Comfort couchette

    This couchette can host up to 4 people and offers plenty of amenities, including a toiletry kit, bedding, and breakfast served in the morning.

    • SeatSeatFold-down table
    • BarBarMinibar
    • ReadingReadingReading light
    • LuggageLuggageLuggage storage
    • PlugPlugPower sockets
    • PlugPlugUSB sockets
    • OvernightOvernightBedding
    • CoffeeCoffeeBreakfast
    • BarBarBottle of water
    • WashbasinWashbasinToiletries
    • LegRoomLegRoomMore legroom
    • ReceiptReceiptFree magazines/newspapers
    • PlusPlusClothes hanger
    • Alarm clockAlarm clockWakeup service
    • WashbasinWashbasinPrivate bathroom
    • BarBarWelcome drink
    • ShowPasswordShowPasswordMirror

      Deluxe cabin Relax

      In this cabin, you'll enjoy a whole breakfast menu, a wake-up service and a comfier bed. Single, double or 3-berth compartments are available.

      • SeatSeatFold-down table
      • BarBarMinibar
      • ReadingReadingReading light
      • LuggageLuggageLuggage storage
      • PlugPlugPower sockets
      • PlugPlugUSB sockets
      • OvernightOvernightBedding
      • CoffeeCoffeeBreakfast
      • BarBarBottle of water
      • WashbasinWashbasinToiletries
      • LegRoomLegRoomMore legroom
      • ReceiptReceiptFree magazines/newspapers
      • PlusPlusClothes hanger
      • Alarm clockAlarm clockWakeup service
      • WashbasinWashbasinPrivate bathroom
      • BarBarWelcome drink
      • ShowPasswordShowPasswordMirror

        Excelsior cabin Superior

        The Excelsior cabin Superior can host up to 2 people. Enjoy the perks of the Deluxe cabin Relax, as well as a welcome drink and a private bathroom with washbasin, shower and mirror.

        • SeatSeatFold-down table
        • BarBarMinibar
        • ReadingReadingReading light
        • LuggageLuggageLuggage storage
        • PlugPlugPower sockets
        • PlugPlugUSB sockets
        • OvernightOvernightBedding
        • CoffeeCoffeeBreakfast
        • BarBarBottle of water
        • WashbasinWashbasinToiletries
        • LegRoomLegRoomMore legroom
        • ReceiptReceiptFree magazines/newspapers
        • PlusPlusClothes hanger
        • Alarm clockAlarm clockWakeup service
        • WashbasinWashbasinPrivate bathroom
        • BarBarWelcome drink
        • ShowPasswordShowPasswordMirror

          What are the onboard services on Intercity Notte (night trains)?

          Discover more about the onboard services offered on trains from Palermo Centrale to Milan Central Station.

          LuggageLuggageWhat luggage limits are there?
          • You can take your bags on board Trenitalia's Intercity Notte trains free of charge.
          • In most cases, there are no luggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your luggage is compatible with the space available on board.
          RestaurantRestaurantWhat food and drink is available?

          A minibar trolley service is available on all Intercity Notte trains – you can choose from a wide range of snacks and drinks. Vegan, gluten-free and lactose-free options are available too.

          WiFiWiFiWhat onboard entertainment is available?

          Unfortunately, free WiFi is not available on Intercity Notte trains.

          ChildPassengerChildPassengerWhat facilities are there for travel with children?
          • Children under 4 can travel for free if a seat is not assigned to them. If they do have a seat, they can get 50% off Base tickets (standard fare).
          • Children aged 4-14 also get 50% off, or 30% off if they’re travelling in the Comfort couchette or Deluxe cabin Relax.
          ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?
          • You can take your folding bike with you if it’s stored in one of the dedicated luggage spaces.
          • If you have a traditional bike, you’ll need to disassemble it and place it in a bag that is not larger than 80 x 110 x 45cm.
          PetPetCan I bring pets on board?
          • Small pets are allowed on board free of charge, if they’re placed in a carrier or cage of max dimensions of 70 x 30 x 50cm. You’ll need to buy a ticket for the whole compartment.
          • Bigger dogs are allowed on board if they have a ticket – it’s usually 50% off the Base ticket (standard fare).
          WheelchairWheelchairWhat special assistance is available?

          Intercity Notte trains have a coach with designated spaces for 2 passengers with a wheelchair and 2 companions. You’ll find a wheelchair symbol outside the coach.

          InfoInfoWhat else do I need to know?

          Depending on the class you’ll be travelling in, you’ll get to enjoy additional perks, including a wake-up service, breakfast, bedding and more.

          How do I find cheap train tickets from Palermo Centrale to Milan Central Station?

          If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

          1. Book in advance

          The price of train tickets from Palermo Centrale to Milan Central Station starts at £60.28§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

          2. Be flexible with your travel times

          If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

          3. Buy a rail pass

          If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

          4. Choose a slower or connecting train

          On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

          5. Look out for train ticket sales and discounts

          Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

          6. Take a night train

          Save on accommodation and use the night to travel by sleeper train to your next destination.

          For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

          §Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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