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Take the train from Pisa to Palermo Centrale in 13 hours 23 minutes

If you want to travel from Pisa to Palermo Centrale by train, you've come to the right place.

You can expect the journey from Pisa to Palermo Centrale by train to take around 15 hours 40 minutes. If you want to get there as quickly as possible, it can take as little as 13 hours 23 minutes on the fastest services. You’ll usually find around 26 trains per day running on this route, which spans 417 miles (671 km). There’s no need for any changes along the way, as there are direct trains available to Palermo Centrale. Trenitalia trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Palermo Centrale.

You can save money on train tickets from Pisa to Palermo Centrale if you book in Use our Journey Planner at the top of the page to search for cheap ticket prices – we'll show you how much you can save on train tickets from Pisa to Palermo Centrale if you book in advance.. Use our Journey Planner at the top of the page to compare ticket prices and get the cheapest fares.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Trains to Palermo Centrale from Pisa

First train

02:21

Last train

23:59

Departure stationPisa
Arrival stationPalermo Centrale
Journey time

From 13h 23m

Distance

417 miles (671 km)

Frequency

26 trains per day

Changes

Direct trains available

Train and bus operators

Trenitalia

What do people frequently ask about the train journey from Pisa to Palermo Centrale?

Want to know more about your journey from Pisa to Palermo Centrale? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Pisa to Palermo Centrale?

You can get from Pisa to Palermo Centrale by train in 15 hours and 40 minutes on average, with the fastest journeys taking just 13 hours and 23 minutes. Check out our Journey Planner for more details.

How long does the train from Pisa to Palermo Centrale take?

The average journey time by train between Pisa and Palermo Centrale is 15 hours and 40 minutes, with around 26 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

What's the fastest journey time between Pisa and Palermo Centrale by train?

The fastest journey time by train from Pisa to Palermo Centrale is 13 hours and 23 minutes.

Can you take a train directly from Pisa to Palermo Centrale?

Yes, it is possible to travel from Pisa to Palermo Centrale without having to change trains. There is 1 direct train from Pisa to Palermo Centrale each day. However, there may be fewer direct services available depending on your exact departure date.

What are the train times from Pisa to Palermo Centrale?

Check out the next trains departing from Pisa to Palermo Centrale for Tuesday 14th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
13:0706:5217h 45m, 3 changes
14:0906:5216h 43m, 4 changes
16:0708:2216h 15m, 1 change
16:0708:2216h 15m, 2 changes
16:3208:2215h 50m, 2 changes
16:5408:2215h 28m, 3 changes
17:3208:2214h 50m, 3 changes
18:0908:2214h 13m, 4 changes
18:1110:0115h 50m, 3 changes
18:1110:5716h 46m, 1 change

Trenitalia trains from Pisa to Palermo Centrale

You can travel from Pisa to Palermo Centrale on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

What Intercity Notte (night trains) classes are there from Pisa to Palermo Centrale?

Compare the different travel classes offered by Intercity Notte (night trains) when travelling from Pisa to Palermo Centrale.

What are the onboard services on Intercity Notte (night trains)?

Discover more about the onboard services offered on trains from Pisa to Palermo Centrale.

LuggageLuggageWhat luggage limits are there?
  • You can take your bags on board Trenitalia's Intercity Notte trains free of charge.
  • In most cases, there are no luggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your luggage is compatible with the space available on board.
RestaurantRestaurantWhat food and drink is available?

A minibar trolley service is available on all Intercity Notte trains – you can choose from a wide range of snacks and drinks. Vegan, gluten-free and lactose-free options are available too.

WiFiWiFiWhat onboard entertainment is available?

Unfortunately, free WiFi is not available on Intercity Notte trains.

ChildPassengerChildPassengerWhat facilities are there for travel with children?
  • Children under 4 can travel for free if a seat is not assigned to them. If they do have a seat, they can get 50% off Base tickets (standard fare).
  • Children aged 4-14 also get 50% off, or 30% off if they’re travelling in the Comfort couchette or Deluxe cabin Relax.
ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?
  • You can take your folding bike with you if it’s stored in one of the dedicated luggage spaces.
  • If you have a traditional bike, you’ll need to disassemble it and place it in a bag that is not larger than 80 x 110 x 45cm.
PetPetCan I bring pets on board?
  • Small pets are allowed on board free of charge, if they’re placed in a carrier or cage of max dimensions of 70 x 30 x 50cm. You’ll need to buy a ticket for the whole compartment.
  • Bigger dogs are allowed on board if they have a ticket – it’s usually 50% off the Base ticket (standard fare).
WheelchairWheelchairWhat special assistance is available?

Intercity Notte trains have a coach with designated spaces for 2 passengers with a wheelchair and 2 companions. You’ll find a wheelchair symbol outside the coach.

InfoInfoWhat else do I need to know?

Depending on the class you’ll be travelling in, you’ll get to enjoy additional perks, including a wake-up service, breakfast, bedding and more.

How do I find cheap train tickets from Pisa to Palermo Centrale?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Pisa to Palermo Centrale starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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