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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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Taking the train from La Spezia Centrale to Palermo Centrale in 14 hours 23 minutes

Thinking about taking the train from La Spezia Centrale to Palermo Centrale? We’ve got you covered.

It usually takes around 16 hours 43 minutes to travel the 454 miles (731 km) from La Spezia Centrale to Palermo Centrale by train, although you can get there in as little as 14 hours 23 minutes on the fastest services. You’ll normally find around 18 trains per day running on this route. You won’t need to worry about making any changes along the way either as direct trains are available. You can travel with Trenitalia trains during your journey, as they are the main operator of services on this route.

Train tickets from La Spezia Centrale to Palermo Centrale start from £114.42 when you book in advance, which can be cheaper than buying them on the day. Start a search in our Journey Planner to check out the latest prices.

Keen to book your train tickets to Palermo Centrale? No need to wait, start a search with us today! If you want to find out a bit more about the journey first, you can find our train timetable below, tips on booking cheap tickets and our FAQs, including first and last train times.

Trains to Palermo Centrale from La Spezia Centrale

It takes an average of 16h 43m to travel from La Spezia Centrale to Palermo Centrale by train, over a distance of around 454 miles (731 km). There are normally 18 trains per day travelling from La Spezia Centrale to Palermo Centrale and tickets for this journey start from £114.42 when you book in advance.

First train

01:27

Last train

23:09

Departure stationLa Spezia Centrale
Arrival stationPalermo Centrale
Journey time

From 14h 23m

Distance

454 miles (731 km)

Frequency

18 trains per day

Changes

Direct trains available

Price

From £114.42

Train and bus operators

Trenitalia

What do people frequently ask about the train journey from La Spezia Centrale to Palermo Centrale?

Want to know more about your journey from La Spezia Centrale to Palermo Centrale? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from La Spezia Centrale to Palermo Centrale?

You can get from La Spezia Centrale to Palermo Centrale by train in 16 hours and 43 minutes on average, with the fastest journeys taking just 14 hours and 23 minutes. Check out our Journey Planner for more details.

How long does the train from La Spezia Centrale to Palermo Centrale take?

The average journey time by train between La Spezia Centrale and Palermo Centrale is 16 hours and 43 minutes, with around 18 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

How much does the train from La Spezia Centrale to Palermo Centrale cost?

Train tickets from La Spezia Centrale to Palermo Centrale can start from as little as £114.42 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending on the time of day, route and class you book.

What's the fastest journey time between La Spezia Centrale and Palermo Centrale by train?

The fastest journey time by train from La Spezia Centrale to Palermo Centrale is 14 hours and 23 minutes.

What are the train times from La Spezia Centrale to Palermo Centrale?

Check out the next trains departing from La Spezia Centrale to Palermo Centrale for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:3221:5514h 23m, 3 changes
12:1606:5218h 36m, 3 changes
12:5506:5217h 57m, 4 changes
15:1608:2217h 6m, 1 change
15:1608:2217h 6m, 2 changes
15:4008:2216h 42m, 3 changes
16:2408:2215h 58m, 5 changes
17:1610:0116h 45m, 3 changes
17:1610:5717h 41m, 1 change
17:1610:5717h 41m, 2 changes

Trenitalia trains from La Spezia Centrale to Palermo Centrale

You can travel from La Spezia Centrale to Palermo Centrale on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

What Intercity Notte (night trains) classes are there from La Spezia Centrale to Palermo Centrale?

Compare the different travel classes offered by Intercity Notte (night trains) when travelling from La Spezia Centrale to Palermo Centrale.

What are the onboard services on Intercity Notte (night trains)?

Discover more about the onboard services offered on trains from La Spezia Centrale to Palermo Centrale.

LuggageLuggageWhat luggage limits are there?
  • You can take your bags on board Trenitalia's Intercity Notte trains free of charge.
  • In most cases, there are no luggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your luggage is compatible with the space available on board.
RestaurantRestaurantWhat food and drink is available?

A minibar trolley service is available on all Intercity Notte trains – you can choose from a wide range of snacks and drinks. Vegan, gluten-free and lactose-free options are available too.

WiFiWiFiWhat onboard entertainment is available?

Unfortunately, free WiFi is not available on Intercity Notte trains.

ChildPassengerChildPassengerWhat facilities are there for travel with children?
  • Children under 4 can travel for free if a seat is not assigned to them. If they do have a seat, they can get 50% off Base tickets (standard fare).
  • Children aged 4-14 also get 50% off, or 30% off if they’re travelling in the Comfort couchette or Deluxe cabin Relax.
ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?
  • You can take your folding bike with you if it’s stored in one of the dedicated luggage spaces.
  • If you have a traditional bike, you’ll need to disassemble it and place it in a bag that is not larger than 80 x 110 x 45cm.
PetPetCan I bring pets on board?
  • Small pets are allowed on board free of charge, if they’re placed in a carrier or cage of max dimensions of 70 x 30 x 50cm. You’ll need to buy a ticket for the whole compartment.
  • Bigger dogs are allowed on board if they have a ticket – it’s usually 50% off the Base ticket (standard fare).
WheelchairWheelchairWhat special assistance is available?

Intercity Notte trains have a coach with designated spaces for 2 passengers with a wheelchair and 2 companions. You’ll find a wheelchair symbol outside the coach.

InfoInfoWhat else do I need to know?

Depending on the class you’ll be travelling in, you’ll get to enjoy additional perks, including a wake-up service, breakfast, bedding and more.

How do I find cheap train tickets from La Spezia Centrale to Palermo Centrale?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from La Spezia Centrale to Palermo Centrale starts at £114.42§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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