Festive French seats are live for travel between Dec 14 to early Jan* – book in advance to save! Ho, ho, gooo…

Skip to contentTrainline homepage
RailcardsBusiness

No tickets in your basket.

Why not plan a trip?

My Bookings
Loading...
Loading...

Trains from Brussels Midi to Prague

Booking.com

ExternalLinkExternalLink

Open Booking.com in a new tab with places to stay on your trip

Eurostar
SNCF

Compare prices from over 270 rail and coach companies in Europe

Icon of trainline-phone-tickets.svg

Buy your tickets with us and easily find them on your phone

Icon of trainline-safe-payments.svg

Safely pay with PayPal, Visa and all international payment cards

Looking for the cheapest date to travel?

Within 7 days

Outbound from

Within 1 month

Outbound from

Within 3 months

Outbound from
Low prices found by our customers
Mon
Tue
Wed
Thu
Fri
Sat
Sun
29301234Today6 Oct7891011121314151617181920212223242526
Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

What customers say about Trainline

Read real reviews from real users

Trustpilot
  1. Home
  2. Train times
  3. Brussels Midi to Prague

Take the train from Brussels Midi to Prague in 10 hours 48 minutes

If you want to travel from Brussels Midi to Prague by train, you've come to the right place.

You can expect the journey from Brussels Midi to Prague by train to take around 13 hours 6 minutes. If you want to get there as quickly as possible, it can take as little as 10 hours 48 minutes on the fastest services. You’ll usually find around 12 trains per day running on this route, which spans 448 miles (720 km). You’ll have to make 2 changes along the way on your journey to Prague. ÖBB trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Prague.

Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from Brussels Midi to Prague start from £73.15 when you book in advance.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Trains to Prague from Brussels Midi

It takes an average of 13h 6m to travel from Brussels Midi to Prague by train, over a distance of around 448 miles (720 km). There are normally 12 trains per day travelling from Brussels Midi to Prague and tickets for this journey start from £73.15 when you book in advance.

First train

06:23

Last train

21:56

Departure stationBrussels Midi
Arrival stationPrague
Journey time

From 10h 48m

Distance

448 miles (720 km)

Frequency

12 trains per day

Changes

2 changes

Price

From £73.15

Train and bus operators

BlaBlaCar Bus, European_Sleeper, Flixbus, ÖBB

What do people frequently ask about the train journey from Brussels Midi to Prague?

Want to know more about your journey from Brussels Midi to Prague? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Prague from Brussels Midi?

To get to Prague from Brussels Midi, why not take the train? With 12 trains per day and an average journey time of 13 hours and 6 minutes, taking the train is a great way to travel. You can also catch the bus from Brussels Midi to Prague. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Brussels Midi to Prague by train?

On average, it takes around 13 hours and 6 minutes to travel from Brussels Midi to Prague by train, although you can get there in 10 hours and 48 minutes on the fastest services. With 12 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Brussels Midi to Prague?

The price of a train ticket from Brussels Midi to Prague can start from as little as £73.15, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Brussels Midi to Prague?

The fastest time a train can travel the 448 miles (720 km) from Brussels Midi to Prague is 10 hours and 48 minutes.

What are the train times from Brussels Midi to Prague?

Check out the next trains departing from Brussels Midi to Prague for Tuesday 14th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:2518:1310h 48m, 3 changes
08:2520:1311h 48m, 2 changes
09:2520:1310h 48m, 3 changes
10:2522:2512h 0m, 5 changes
11:2523:1411h 49m, 2 changes
12:2523:1410h 49m, 3 changes
13:2505:0015h 35m, 5 changes
18:2508:1313h 48m, 2 changes
18:5610:1615h 20m, 6 changes
20:5613:2216h 26m, 5 changes

ÖBB trains from Brussels Midi to Prague

You can travel from Brussels Midi to Prague on ÖBB trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

ÖBB is the major railway company for Austria, subdivided into several subsidiaries, responsible for certain areas of transport, such as long distance and local transport, the operation of postal buses and the transport of goods. Railjet is ÖBB's high-speed train, which travels at speeds of up to 143 mph (230 km/h) and connects the main Austrian cities with Germany, Hungary, Switzerland, the Czech Republic and Italy.

More information

How do I find cheap train tickets from Brussels Midi to Prague?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Brussels Midi to Prague starts at £73.15§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

Europe’s leading train and coach app

We help customers across Europe make more than 172,000 smarter journeys every day.

Get a link