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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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Take the train from Prague to Brussels Midi in 12 hours

If you want to travel from Prague to Brussels Midi by train, you've come to the right place.

You can expect the journey from Prague to Brussels Midi by train to take around 14 hours 50 minutes. If you want to get there as quickly as possible, it can take as little as 12 hours on the fastest services. You’ll usually find around 18 trains per day running on this route, which spans 448 miles (720 km). There’s no need for any changes along the way, as there are direct trains available to Brussels Midi.

Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from Prague to Brussels Midi start from £53.54 when you book in advance.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Prague to Brussels Midi by train

It takes an average of 14h 50m to travel from Prague to Brussels Midi by train, over a distance of around 448 miles (720 km). There are normally 18 trains per day travelling from Prague to Brussels Midi and tickets for this journey start from £53.54 when you book in advance.

First train

03:19

Last train

18:42

Departure station

Prague

Arrival station

Brussels Midi

Journey time

From 12h 0m

Distance

448 miles (720 km)

Frequency

18 trains per day

Changes

Direct trains available

Price

From £53.54

Train and bus operators

Flixbus, European_Sleeper

FAQs about the train journey from Prague to Brussels Midi

Want to know more about your journey from Prague to Brussels Midi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Brussels Midi from Prague?

To get to Brussels Midi from Prague, why not take the train? With 18 trains per day and an average journey time of 14 hours and 50 minutes, taking the train is a great way to travel. You can also catch the bus from Prague to Brussels Midi. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Prague to Brussels Midi by train?

On average, it takes around 14 hours and 50 minutes to travel from Prague to Brussels Midi by train, although you can get there in 12 hours and 0 minutes on the fastest services. With 18 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Prague to Brussels Midi?

The price of a train ticket from Prague to Brussels Midi can start from as little as £53.54, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Prague to Brussels Midi?

The fastest time a train can travel the 448 miles (720 km) from Prague to Brussels Midi is 12 hours and 0 minutes.

Prague to Brussels Midi train times

Check out the next trains departing from Prague to Brussels Midi for Tuesday 6th May 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:3921:0313h 24m, 4 changes
07:3921:1713h 38m, 3 changes
07:3922:0614h 27m, 2 changes
08:3522:0313h 28m, 5 changes
09:3923:1113h 32m, 4 changes
09:3923:1713h 38m, 3 changes
11:4304:4717h 4m, 4 changes
12:3507:0518h 30m, 7 changes
13:4308:0518h 22m, 4 changes
14:3508:0517h 30m, 6 changes

Cheap train tickets from Prague to Brussels Midi

The price of train tickets from Prague to Brussels Midi starts at £53.54 one-way for a Standard Class ticket if you book in advance. Booking on the day is usually more expensive and costs can vary depending on the time of day, route or class.

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Prague to Brussels Midi by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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