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Trains from St-Louis to Milan Central Station

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  3. St-Louis to Milan Central Station

Take the train from St-Louis to Milan Central Station in 4 hours 38 minutes

If you want to travel from St-Louis to Milan Central Station by train, you've come to the right place.

You can expect the journey from St-Louis to Milan Central Station by train to take around 5 hours 12 minutes. If you want to get there as quickly as possible, it can take as little as 4 hours 38 minutes on the fastest services. You’ll usually find around 29 trains per day running on this route, which spans 165 miles (266 km). You’ll have to make 1 change along the way on your journey to Milan Central Station. Trenitalia trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Milan Central Station.

Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from St-Louis to Milan Central Station start from £82.79 when you book in advance.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Trains to Milan Central Station from St-Louis

It takes an average of 5h 12m to travel from St-Louis to Milan Central Station by train, over a distance of around 165 miles (266 km). There are normally 29 trains per day travelling from St-Louis to Milan Central Station and tickets for this journey start from £82.79 when you book in advance.

First train

05:12

Last train

23:15

Departure stationSt-Louis
Arrival stationMilan Central Station
Journey time

From 4h 38m

Distance

165 miles (266 km)

Frequency

29 trains per day

Changes

1 change

Price

From £82.79

Train and bus operators

Trenitalia

What do people frequently ask about the train journey from St-Louis to Milan Central Station?

Want to know more about your journey from St-Louis to Milan Central Station? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from St-Louis to Milan Central Station?

You can travel from St-Louis to Milan Central Station by train in about 5 hours and 12 minutes. With around 29 trains running each day, taking the train is easy. Find out more in our Journey Planner.

How long is the train journey from St-Louis to Milan Central Station?

On average, the train journey from St-Louis to Milan Central Station takes around 5 hours and 12 minutes, with 29 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

How much is the train from St-Louis to Milan Central Station?

Train tickets from St-Louis to Milan Central Station start from as little as £82.79, depending on the time of booking, class of service and type of train. Booking in advance often results in cheaper prices.

What is the fastest train from St-Louis to Milan Central Station?

The fastest trains from St-Louis to Milan Central Station can cover the distance of 165 miles (266 km) in as little as 4 hours and 38 minutes.

What are the train times from St-Louis to Milan Central Station?

Check out the next trains departing from St-Louis to Milan Central Station for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
09:3114:204h 49m, 2 changes
09:3114:535h 22m, 1 change
10:1214:534h 41m, 2 changes
10:4215:204h 38m, 3 changes
11:0115:534h 52m, 2 changes
11:0115:554h 54m, 1 change
11:4216:204h 38m, 2 changes
12:4217:204h 38m, 3 changes
13:0117:534h 52m, 2 changes
13:4218:204h 38m, 2 changes

Trenitalia trains from St-Louis to Milan Central Station

You can travel from St-Louis to Milan Central Station on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

More information

What Trenitalia Eurocity classes are there from St-Louis to Milan Central Station?

Compare the different travel classes offered by Trenitalia Eurocity when travelling from St-Louis to Milan Central Station.

Second Class

From spacious armchairs to at-seat power sockets and reading lights, you’ve got everything you need to enjoy your journey in EuroCity's Second Class.

  • SeatSeatSeat reservation
  • PlugPlugPower sockets
  • PlusPlusClothes hanger
  • ReadingReadingReading light
  • LuggageLuggageLuggage storage
  • WiFiWiFiFree WiFi
  • BarBarBar/restaurant carriage
  • LegRoomLegRoomMore legroom

    First Class

    In addition to all the services available in Second Class, you’ll get to enjoy extra-wide and comfier seats, more legroom, and an at-seat catering service in EuroCity’s First Class:

    • SeatSeatSeat reservation
    • PlugPlugPower sockets
    • PlusPlusClothes hanger
    • ReadingReadingReading light
    • LuggageLuggageLuggage storage
    • WiFiWiFiFree WiFi
    • BarBarBar/restaurant carriage
    • LegRoomLegRoomMore legroom

      What are the onboard services on Trenitalia Eurocity?

      Discover more about the onboard services offered on trains from St-Louis to Milan Central Station.

      LuggageLuggageWhat luggage limits are there?
      • You can take your bags on board Trenitalia's Eurocity trains free of charge.
      • In most cases, there are no luggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your luggage is compatible with the space available on board.
      RestaurantRestaurantWhat food and drink is available?
      • You’ll find a Bar-Bistrò on Eurocity trains that are travelling between Italy, Switzerland and Germany.
      • A minibar trolley service is also available – you can choose from a wide range of snacks and drinks.
      WiFiWiFiWhat onboard entertainment is available?

      Free WiFi is available on Eurocity Giruno trains.

      ChildPassengerChildPassengerWhat facilities are there for travel with children?

      Children under 4 can travel for free if they're accompanied by an adult and don't occupy a seat.

      ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?

      Not all Eurocity trains allow you to take your bike on board – you’ll need to check in advance if you can travel with your bike. If that’s the case, you’ll need to buy a ticket and book your bike space before departure at the ticket office.

      PetPetCan I bring pets on board?

      Guide and assistance dogs can travel for free and don't need a ticket.

      WheelchairWheelchairWhat special assistance is available?

      All of Trenitalia’s Eurocity trains offer dedicated spaces to passengers with disabilities.

      InfoInfoWhat else do I need to know?

      A quiet area (or Area Silenzio) is available on all Eurocity Giruno trains.

      How do I find cheap train tickets from St-Louis to Milan Central Station?

      If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

      1. Book in advance

      The price of train tickets from St-Louis to Milan Central Station starts at £82.79§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

      2. Be flexible with your travel times

      If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

      3. Buy a rail pass

      If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

      4. Choose a slower or connecting train

      On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

      5. Look out for train ticket sales and discounts

      Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

      6. Take a night train

      Save on accommodation and use the night to travel by sleeper train to your next destination.

      For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

      §Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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