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Trains from Prague to Brussels Midi

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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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  3. Prague to Brussels Midi

Take the train from Prague to Brussels Midi in 11 hours

If you want to travel from Prague to Brussels Midi by train, you've come to the right place.

You can expect the journey from Prague to Brussels Midi by train to take around 14 hours 41 minutes. If you want to get there as quickly as possible, it can take as little as 11 hours on the fastest services. You’ll usually find around 13 trains per day running on this route, which spans 448 miles (720 km). There’s no need for any changes along the way, as there are direct trains available to Brussels Midi.

Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from Prague to Brussels Midi start from £119.94 when you book in advance.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Trains to Brussels Midi from Prague

It takes an average of 14h 41m to travel from Prague to Brussels Midi by train, over a distance of around 448 miles (720 km). There are normally 13 trains per day travelling from Prague to Brussels Midi and tickets for this journey start from £119.94 when you book in advance.

First train

05:35

Last train

20:55

Departure stationPrague
Arrival stationBrussels Midi
Journey time

From 11h 0m

Distance

448 miles (720 km)

Frequency

13 trains per day

Changes

Direct trains available

Price

From £119.94

Train and bus operators

European_Sleeper, Flixbus

What do people frequently ask about the train journey from Prague to Brussels Midi?

Want to know more about your journey from Prague to Brussels Midi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Brussels Midi from Prague?

To get to Brussels Midi from Prague, why not take the train? With 13 trains per day and an average journey time of 14 hours and 41 minutes, taking the train is a great way to travel. You can also catch the bus from Prague to Brussels Midi. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Prague to Brussels Midi by train?

On average, it takes around 14 hours and 41 minutes to travel from Prague to Brussels Midi by train, although you can get there in 11 hours and 0 minutes on the fastest services. With 13 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Prague to Brussels Midi?

The price of a train ticket from Prague to Brussels Midi can start from as little as £119.94, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Prague to Brussels Midi?

The fastest time a train can travel the 448 miles (720 km) from Prague to Brussels Midi is 11 hours and 0 minutes.

What are the train times from Prague to Brussels Midi?

Check out the next trains departing from Prague to Brussels Midi for Tuesday 2nd December 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
06:3517:3511h 0m, 4 changes
06:3518:3612h 1m, 2 changes
08:3519:3511h 0m, 4 changes
08:3520:3612h 1m, 2 changes
16:3507:3515h 0m, 4 changes
17:0207:3514h 33m, 5 changes
17:0208:3515h 33m, 3 changes
17:0209:0616h 4m, 1 change
17:0209:3916h 37m, direct
17:4212:3618h 54m, 3 changes

How do I find cheap train tickets from Prague to Brussels Midi?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Prague to Brussels Midi starts at £119.94§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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