Book a Japan autumn by train – browse the full suite of Japan Rail Passes, here.

Skip to contentTrainline homepage
RailcardsBusiness

No tickets in your basket.

Why not plan a trip?

My Bookings
Loading...
Loading...

Trains from Pisa Centrale to Brindisi

Booking.com

ExternalLinkExternalLink

Open Booking.com in a new tab with places to stay on your trip

Trenitalia
Italo

Compare prices from over 270 rail and coach companies in Europe

Icon of trainline-phone-tickets.svg

Buy your tickets with us and easily find them on your phone

Icon of trainline-safe-payments.svg

Safely pay with PayPal, Visa and all international payment cards

Looking for the cheapest date to travel?

Within 7 days

Outbound from

Within 1 month

Outbound from

Within 3 months

Outbound from
Low prices found by our customers
Mon
Tue
Wed
Thu
Fri
Sat
Sun
6Today8 Oct9101112131415161718192021222324252627282930311 Nov2
Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

What customers say about Trainline

Read real reviews from real users

Trustpilot
  1. Home
  2. Train times
  3. Pisa Centrale to Brindisi

About the train journey from Pisa Centrale to Brindisi

Want to travel from Pisa Centrale to Brindisi by train? Start your journey with us.

The train from Pisa Centrale to Brindisi usually takes 10 hours 28 minutes on average to travel 440 miles (709 km), although the quickest services can take as little as 8 hours 11 minutes. You can expect to find 28 trains per day running on this popular route. As there aren’t any direct services running between Pisa Centrale and Brindisi, you’ll need to make 1 change on your way to Brindisi.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Pisa Centrale to Brindisi in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save, as advance tickets start from £66.21.

Keep reading for more information about the train journey to Brindisi, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Trains to Brindisi from Pisa Centrale

It takes an average of 10h 28m to travel from Pisa Centrale to Brindisi by train, over a distance of around 440 miles (709 km). There are normally 28 trains per day travelling from Pisa Centrale to Brindisi and tickets for this journey start from £66.21 when you book in advance.

First train

02:21

Last train

20:42

Departure stationPisa Centrale
Arrival stationBrindisi
Journey time

From 8h 11m

Distance

440 miles (709 km)

Frequency

28 trains per day

Changes

1 change

Price

From £66.21

Train and bus operators

Marino

What do people frequently ask about the train journey from Pisa Centrale to Brindisi?

Want to know more about your journey from Pisa Centrale to Brindisi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Pisa Centrale to Brindisi?

You can get from Pisa Centrale to Brindisi by train in 10 hours and 28 minutes on average, with the fastest journeys taking just 8 hours and 11 minutes. You can also take the bus from Pisa Centrale to Brindisi. Check out our Journey Planner for more details.

How long does the train from Pisa Centrale to Brindisi take?

The average journey time by train between Pisa Centrale and Brindisi is 10 hours and 28 minutes, with around 28 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

How much does the train from Pisa Centrale to Brindisi cost?

Train tickets from Pisa Centrale to Brindisi can start from as little as £66.21 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending on the time of day, route and class you book.

What's the fastest journey time between Pisa Centrale and Brindisi by train?

The fastest journey time by train from Pisa Centrale to Brindisi is 8 hours and 11 minutes.

What are the train times from Pisa Centrale to Brindisi?

Check out the next trains departing from Pisa Centrale to Brindisi for Tuesday 14th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
08:3217:248h 52m, 2 changes
08:5419:0810h 14m, 3 changes
08:5419:0810h 14m, 2 changes
09:0118:149h 13m, 3 changes
09:3219:089h 36m, 3 changes
10:1119:159h 4m, 1 change
10:3019:158h 45m, 2 changes
11:3220:208h 48m, 2 changes
12:0921:329h 23m, 2 changes
13:0722:209h 13m, 1 change

How do I find cheap train tickets from Pisa Centrale to Brindisi?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Pisa Centrale to Brindisi starts at £66.21§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

Europe’s leading train and coach app

We help customers across Europe make more than 172,000 smarter journeys every day.

Get a link