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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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Travel from Siena to Palermo by train in 13 hours 37 minutes

If you want to know more about the journey from Siena to Palermo by train, look no further!

The average journey time from Siena to Palermo by train is 16 hours 43 minutes, although on the fastest services it can take just 13 hours 37 minutes. Around 17 trains per day travel the 375 miles (604 km) between these two destinations. You'll need to make 1 change along the way to Palermo.

Book train tickets from Siena to Palermo in advance instead of buying them on the day and they can start from £117.98. We'll always highlight the cheapest prices when you search in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Siena to Palermo by train

It takes an average of 16h 43m to travel from Siena to Palermo by train, over a distance of around 375 miles (604 km). There are normally 17 trains per day travelling from Siena to Palermo and tickets for this journey start from £117.98 when you book in advance.

First train

05:00

Last train

21:40

Departure station

Siena

Arrival station

Palermo

Journey time

From 13h 37m

Distance

375 miles (604 km)

Frequency

17 trains per day

Changes

1 change

Price

From £117.98

Train and bus operators

Flixbus

FAQs about the train journey from Siena to Palermo

Want to know more about your journey from Siena to Palermo? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Siena to Palermo?

You can get from Siena to Palermo by train in 16 hours and 43 minutes on average, with the fastest journeys taking just 13 hours and 37 minutes. Check out our Journey Planner for more details.

How long does the train from Siena to Palermo take?

The average journey time by train between Siena and Palermo is 16 hours and 43 minutes, with around 17 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

How much does the train from Siena to Palermo cost?

Train tickets from Siena to Palermo can start from as little as £117.98 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending on the time of day, route and class you book.

What's the fastest journey time between Siena and Palermo by train?

The fastest journey time by train from Siena to Palermo is 13 hours and 37 minutes.

Siena to Palermo train times

Check out the next trains departing from Siena to Palermo for Tuesday 6th May 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
07:4821:5014h 2m, 3 changes
08:1821:5513h 37m, 3 changes
11:1806:5219h 34m, 3 changes
12:3206:5218h 20m, 4 changes
12:4106:5218h 11m, 5 changes
15:1808:2217h 4m, 2 changes
15:4108:2216h 41m, 3 changes
16:1808:2216h 4m, 3 changes
18:1810:0115h 43m, 4 changes
18:1811:3117h 13m, 2 changes

Cheap train tickets from Siena to Palermo

The price of train tickets from Siena to Palermo starts at £117.98 one-way for a Standard Class ticket if you book in advance. Booking on the day is usually more expensive and costs can vary depending on the time of day, route or class.

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Siena to Palermo by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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