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Travel from Palermo to Siena by train in 13 hours 16 minutes

If you want to know more about the journey from Palermo to Siena by train, look no further!

The average journey time from Palermo to Siena by train is 16 hours 45 minutes, although on the fastest services it can take just 13 hours 16 minutes. Around 15 trains per day travel the 375 miles (604 km) between these two destinations. You'll need to make 2 changes along the way to Siena.

Book train tickets from Palermo to Siena in advance instead of buying them on the day and you'll snap up the cheapest fares. You can check prices from Palermo to Siena in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Trains to Siena from Palermo

First train

05:07

Last train

20:25

Departure stationPalermo
Arrival stationSiena
Journey time

From 13h 16m

Distance

375 miles (604 km)

Frequency

15 trains per day

Changes

2 changes

Train and bus operators

Flixbus

What do people frequently ask about the train journey from Palermo to Siena?

Want to know more about your journey from Palermo to Siena? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Palermo to Siena?

You can get from Palermo to Siena by train in 16 hours and 45 minutes on average, with the fastest journeys taking just 13 hours and 16 minutes. Check out our Journey Planner for more details.

How long does the train from Palermo to Siena take?

The average journey time by train between Palermo and Siena is 16 hours and 45 minutes, with around 15 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

What's the fastest journey time between Palermo and Siena by train?

The fastest journey time by train from Palermo to Siena is 13 hours and 16 minutes.

Can you take a train directly from Palermo to Siena?

No, there are no direct train services from Palermo to Siena. Travelling from Palermo to Siena by train will require a minimum of 2 changes.

What are the train times from Palermo to Siena?

Check out the next trains departing from Palermo to Siena for Tuesday 14th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
06:0520:1614h 11m, 4 changes
07:1320:3913h 26m, 4 changes
09:1504:4919h 34m, 2 changes
09:1504:4919h 34m, 3 changes
11:5806:5518h 57m, 1 change
11:5806:5518h 57m, 3 changes
15:3209:1617h 44m, 6 changes
15:3209:4018h 8m, 4 changes
17:4810:4016h 52m, 2 changes
17:4810:4016h 52m, 3 changes

How do I find cheap train tickets from Palermo to Siena?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Palermo to Siena starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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