SNCF First Class seats from Paris on sale from just £57! Book now

Business

No tickets in your basket.

Why not plan a trip?

My Bookings
Loading...
Loading...
Trenitalia
Italo

Compare prices from over 270 rail and coach companies in Europe

Icon of trainline-phone-tickets.svg

Buy your tickets with us and easily find them on your phone

Icon of trainline-safe-payments.svg

Safely pay with PayPal, Visa and all international payment cards

Popular in Brussels Midi

Let's do this trip right

What customers say about Trainline

Read real reviews from real users

About the train journey from Isernia to Brussels Midi

Want to travel from Isernia to Brussels Midi by train? Start your journey with us.

The train from Isernia to Brussels Midi usually takes 21 hours 41 minutes on average to travel 793 miles (1276 km), although the quickest services can take as little as 16 hours 7 minutes. You can expect to find 7 trains per day running on this popular route. As there aren’t any direct services running between Isernia and Brussels Midi, you’ll need to make 3 changes on your way to Brussels Midi.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Isernia to Brussels Midi in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save!

Keep reading for more information about the train journey to Brussels Midi, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Isernia to Brussels Midi by train

First train

06:40

Last train

20:32

Departure station

Isernia

Arrival station

Brussels Midi

Journey time

From 16h 7m

Distance

793 miles (1276 km)

Frequency

7 trains per day

Changes

3 changes

FAQs about the train journey from Isernia to Brussels Midi

Want to know more about your journey from Isernia to Brussels Midi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you get to Brussels Midi from Isernia?

To travel to Brussels Midi from Isernia, you can take the train - on average, the journey takes around 21 hours and 41 minutes, though the fastest trains can take 16 hours and 7 minutes. Use our Journey Planner to get more information.

How long is the train ride from Isernia to Brussels Midi?

Trains from Isernia to Brussels Midi take an average of 21 hours and 41 minutes, although on the fastest services it can take just 16 hours and 7 minutes. You'll usually find 7 trains per day on this route, so use our Journey Planner to check specific dates as times may vary.

What is the quickest journey time between Isernia and Brussels Midi by train?

The quickest journey time between Isernia and Brussels Midi by train is 16 hours and 7 minutes.

Are there direct trains from Isernia to Brussels Midi?

No, there are no direct trains running from Isernia to Brussels Midi, you’ll usually need to make at least 3 changes during the journey.

Isernia to Brussels Midi train times

Check out the next trains departing from Isernia to Brussels Midi for Tuesday 6th May 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
05:4021:4716h 7m, 7 changes
07:3806:4423h 6m, 3 changes
12:2810:1721h 49m, 6 changes
14:0312:1722h 14m, 6 changes
14:0312:4422h 41m, 6 changes
14:0314:4424h 41m, 3 changes
19:3216:4321h 11m, 5 changes

Cheap train tickets from Isernia to Brussels Midi

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Isernia to Brussels Midi by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

Europe’s leading train and coach app

We help customers across Europe make more than 172,000 smarter journeys every day.