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Travelling from Florence to Isernia by train

Looking to travel from Florence to Isernia by train? You've come to the right place!

On average, it takes around 6 hours 23 minutes to travel from Florence to Isernia by train, the fastest services can get you there in as little as 3 hours 59 minutes though. You'll usually find 21 trains per day running along the 213 miles (343 km) route between these two destinations. You’ll need to make 1 change during the journey to Isernia, as there currently aren't any direct services on this route.

Plan your trip ahead and book your train tickets in advance if you want to snap up the cheapest fares. Just start a search in our Journey Planner to view the latest prices for trains from Florence to Isernia.

If you’re feeling ready to book, start looking for cheap train tickets with us today. Keep reading for more information on the journey to Isernia by train, including our timetable where you can view first and last train times.

Florence to Isernia by train

First train

07:05

Last train

22:43

Departure station

Florence

Arrival station

Isernia

Journey time

From 3h 59m

Distance

213 miles (343 km)

Frequency

21 trains per day

Changes

1 change

Train and bus operators

Flixbus

FAQs about the train journey from Florence to Isernia

Want to know more about your journey from Florence to Isernia? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Isernia from Florence?

To get to Isernia from Florence, why not take the train? With 21 trains per day and an average journey time of 6 hours and 23 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Florence to Isernia by train?

On average, it takes around 6 hours and 23 minutes to travel from Florence to Isernia by train, although you can get there in 3 hours and 59 minutes on the fastest services. With 21 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How fast can trains travel from Florence to Isernia?

The fastest time a train can travel the 213 miles (343 km) from Florence to Isernia is 3 hours and 59 minutes.

Are there any direct trains from Florence to Isernia?

There are no direct trains that run between Florence and Isernia. You’ll need to make at least 1 change along the way.

Florence to Isernia train times

Check out the next trains departing from Florence to Isernia for Tuesday 6th May 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
12:1418:055h 51m, 1 change
12:4318:055h 22m, 1 change
13:1418:054h 51m, 2 changes
14:1419:555h 41m, 1 change
14:2818:544h 26m, 2 changes
14:4818:544h 6m, 1 change
15:1419:554h 41m, 2 changes
15:1420:405h 26m, 1 change
15:2820:274h 59m, 1 change
17:1421:274h 13m, 1 change

Cheap train tickets from Florence to Isernia

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Florence to Isernia by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

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