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Travel from Firenze Santa Maria Novella to Sant’Ambrogio by train in 3 hours 57 minutes

If you want to know more about the journey from Firenze Santa Maria Novella to Sant’Ambrogio by train, look no further!

The average journey time from Firenze Santa Maria Novella to Sant’Ambrogio by train is 6 hours 15 minutes, although on the fastest services it can take just 3 hours 57 minutes. Around 20 trains per day travel the 212 miles (342 km) between these two destinations. You'll need to make 1 change along the way to Sant’Ambrogio.

Book train tickets from Firenze Santa Maria Novella to Sant’Ambrogio in advance instead of buying them on the day and you'll snap up the cheapest fares. You can check prices from Firenze Santa Maria Novella to Sant’Ambrogio in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Trains to Sant’Ambrogio from Firenze Santa Maria Novella

First train

00:40

Last train

22:09

Departure stationFirenze Santa Maria Novella
Arrival stationSant’Ambrogio
Journey time

From 3h 57m

Distance

212 miles (342 km)

Frequency

20 trains per day

Changes

1 change

What do people frequently ask about the train journey from Firenze Santa Maria Novella to Sant’Ambrogio?

Want to know more about your journey from Firenze Santa Maria Novella to Sant’Ambrogio? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Sant’Ambrogio from Firenze Santa Maria Novella?

To get to Sant’Ambrogio from Firenze Santa Maria Novella, why not take the train? With 20 trains per day and an average journey time of 6 hours and 15 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Firenze Santa Maria Novella to Sant’Ambrogio by train?

On average, it takes around 6 hours and 15 minutes to travel from Firenze Santa Maria Novella to Sant’Ambrogio by train, although you can get there in 3 hours and 57 minutes on the fastest services. With 20 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How fast can trains travel from Firenze Santa Maria Novella to Sant’Ambrogio?

The fastest time a train can travel the 212 miles (342 km) from Firenze Santa Maria Novella to Sant’Ambrogio is 3 hours and 57 minutes.

Are there any direct trains from Firenze Santa Maria Novella to Sant’Ambrogio?

There are no direct trains that run between Firenze Santa Maria Novella and Sant’Ambrogio. You’ll need to make at least 1 change along the way.

What are the train times from Firenze Santa Maria Novella to Sant’Ambrogio?

Check out the next trains departing from Firenze Santa Maria Novella to Sant’Ambrogio for Tuesday 28th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
10:1014:184h 8m, 1 change
11:1015:184h 8m, 1 change
11:5516:184h 23m, 1 change
12:5517:184h 23m, 1 change
13:5517:523h 57m, 1 change
14:5519:184h 23m, 2 changes
16:1020:184h 8m, 1 change
16:5521:184h 23m, 1 change
17:5522:184h 23m, 1 change
19:1004:189h 8m, 1 change

How do I find cheap train tickets from Firenze Santa Maria Novella to Sant’Ambrogio?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Firenze Santa Maria Novella to Sant’Ambrogio starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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