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Trains from Prague to Milan Central Station

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  3. Prague to Milan Central Station

Travel from Prague to Milan Central Station by train in 13 hours 10 minutes

If you want to know more about the journey from Prague to Milan Central Station by train, look no further!

The average journey time from Prague to Milan Central Station by train is 16 hours 15 minutes, although on the fastest services it can take just 13 hours 10 minutes. Around 16 trains per day travel the 400 miles (644 km) between these two destinations. You'll need to make 1 change along the way to Milan Central Station. As the main train operator on this route, you'll probably be travelling on a Regiojet service for all or at least part of your journey to Milan Central Station.

Book train tickets from Prague to Milan Central Station in advance instead of buying them on the day and they can start from £105.06. We'll always highlight the cheapest prices when you search in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Trains to Milan Central Station from Prague

It takes an average of 16h 15m to travel from Prague to Milan Central Station by train, over a distance of around 400 miles (644 km). There are normally 16 trains per day travelling from Prague to Milan Central Station and tickets for this journey start from £105.06 when you book in advance.

First train

00:36

Last train

18:42

Departure stationPrague
Arrival stationMilan Central Station
Journey time

From 13h 10m

Distance

400 miles (644 km)

Frequency

16 trains per day

Changes

1 change

Price

From £105.06

Train and bus operators

Flixbus, Regiojet

What do people frequently ask about the train journey from Prague to Milan Central Station?

Want to know more about your journey from Prague to Milan Central Station? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Prague to Milan Central Station?

You can travel from Prague to Milan Central Station by train in about 16 hours and 15 minutes. With around 16 trains running each day, taking the train is easy. Find out more in our Journey Planner.

How long is the train journey from Prague to Milan Central Station?

On average, the train journey from Prague to Milan Central Station takes around 16 hours and 15 minutes, with 16 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

How much is the train from Prague to Milan Central Station?

Train tickets from Prague to Milan Central Station start from as little as £105.06, depending on the time of booking, class of service and type of train. Booking in advance often results in cheaper prices.

What is the fastest train from Prague to Milan Central Station?

The fastest trains from Prague to Milan Central Station can cover the distance of 400 miles (644 km) in as little as 13 hours and 10 minutes.

What are the train times from Prague to Milan Central Station?

Check out the next trains departing from Prague to Milan Central Station for Tuesday 7th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
02:1917:5315h 34m, 4 changes
04:3517:5513h 20m, 2 changes
06:3519:4513h 10m, 2 changes
08:3523:0514h 30m, 3 changes
10:3504:2017h 45m, 4 changes
13:4207:5018h 8m, 2 changes
14:2007:5017h 30m, 4 changes
14:3509:2018h 45m, 6 changes
17:3909:5016h 11m, 3 changes
17:3910:5017h 11m, 2 changes

What RegioJet classes are there from Prague to Milan Central Station?

Compare the different travel classes offered by RegioJet when travelling from Prague to Milan Central Station.

Low cost

Although Low Cost is the cheapest option offered by RegioJet, this class boasts a variety of free services, including WiFi, newspapers and an entertainment platform.

  • WiFiWiFiFree WiFi
  • ReceiptReceiptFree magazines/newspapers
  • ETicketbarcodeETicketbarcodeOnboard app service
  • RestaurantRestaurantCatering at your seat
  • PlugPlugPower sockets
  • LegRoomLegRoomAdjustable seats/footrests
  • SeatSeatFold-down table
  • LeatherSeatLeatherSeatLeather seats
  • QuietZoneQuietZoneQuiet area
  • LegRoomLegRoomMore legroom

    Standard

    In addition to the amenities of the Economy class, you will also enjoy Italian coffee, complimentary tea and juice, power sockets and adjustable seats.

    • WiFiWiFiFree WiFi
    • ReceiptReceiptFree magazines/newspapers
    • ETicketbarcodeETicketbarcodeOnboard app service
    • RestaurantRestaurantCatering at your seat
    • PlugPlugPower sockets
    • LegRoomLegRoomAdjustable seats/footrests
    • SeatSeatFold-down table
    • LeatherSeatLeatherSeatLeather seats
    • QuietZoneQuietZoneQuiet area
    • LegRoomLegRoomMore legroom

      Relax

      In the Relax class, you’ll take advantage of all the amenities in Standard and Low-Cost, as well as large fold-down tables, comfy leather seats and individual seating.

      • WiFiWiFiFree WiFi
      • ReceiptReceiptFree magazines/newspapers
      • ETicketbarcodeETicketbarcodeOnboard app service
      • RestaurantRestaurantCatering at your seat
      • PlugPlugPower sockets
      • LegRoomLegRoomAdjustable seats/footrests
      • SeatSeatFold-down table
      • LeatherSeatLeatherSeatLeather seats
      • QuietZoneQuietZoneQuiet area
      • LegRoomLegRoomMore legroom

        Business

        Travel in RegioJet’s Business class for a premium experience. During your journey, you can rest or work quietly in the quiet carriage and enjoy spacious seats.

        • WiFiWiFiFree WiFi
        • ReceiptReceiptFree magazines/newspapers
        • ETicketbarcodeETicketbarcodeOnboard app service
        • RestaurantRestaurantCatering at your seat
        • PlugPlugPower sockets
        • LegRoomLegRoomAdjustable seats/footrests
        • SeatSeatFold-down table
        • LeatherSeatLeatherSeatLeather seats
        • QuietZoneQuietZoneQuiet area
        • LegRoomLegRoomMore legroom

          What are the onboard services on RegioJet?

          Discover more about the onboard services offered on trains from Prague to Milan Central Station.

          LuggageLuggageWhat luggage limits are there?

          There are no weight limits when it comes to luggage on Regiojet trains - you can take what you like, so long as you can carry it by yourself.

          RestaurantRestaurantWhat food and drink is available?

          Choose from a wide range of drinks, snacks and light bites on board - you'll find the full menu on the Regiojet app. A free bottle of water is available for all customers. For passengers travelling with Relax or Business Class tickets, you'll also be offered a free Italian coffee or mint tea (made with real mint leaves) when on board.

          WiFiWiFiWhat onboard entertainment is available?

          Free WiFi is available on board. You can access the entertainment portal using the Regiojet app, or through the built-in screens on more modern Regiojet trains.

          ChildPassengerChildPassengerWhat facilities are there for travel with children?

          Pushchairs should be folded up to be taken on board. If this isn't possible, you must store your pushchair at the front or back of the carriage.

          ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?

          Bicycles cannot be transported on Regiojet trains.

          PetPetCan I bring pets on board?

          It's possible to bring small pets on board Regiojet trains in suitable carriers. Pets are not allowed in sleeper carriages or couchettes. Guide dogs of all sizes are permitted on board.

          WheelchairWheelchairWhat special assistance is available?

          Dedicated wheelchair spaces are available on Regiojet trains.

          How do I find cheap train tickets from Prague to Milan Central Station?

          If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

          1. Book in advance

          The price of train tickets from Prague to Milan Central Station starts at £105.06§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

          2. Be flexible with your travel times

          If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

          3. Buy a rail pass

          If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

          4. Choose a slower or connecting train

          On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

          5. Look out for train ticket sales and discounts

          Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

          6. Take a night train

          Save on accommodation and use the night to travel by sleeper train to your next destination.

          For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

          §Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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