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Trains from Frankfurt (Main) to Palermo Centrale

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  1. Home
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  3. Frankfurt (Main) to Palermo Centrale

Taking the train from Frankfurt (Main) to Palermo Centrale in 23 hours 4 minutes

Thinking about taking the train from Frankfurt (Main) to Palermo Centrale? We’ve got you covered.

It usually takes around 26 hours 2 minutes to travel the 861 miles (1385 km) from Frankfurt (Main) to Palermo Centrale by train, although you can get there in as little as 23 hours 4 minutes on the fastest services. You’ll normally find around 16 trains per day running on this route. You’ll need to make 2 changes along the way as there aren't any direct services on this line.

Train tickets from Frankfurt (Main) to Palermo Centrale start from £140.03 when you book in advance, which can be cheaper than buying them on the day. Start a search in our Journey Planner to check out the latest prices.

Keen to book your train tickets to Palermo Centrale? No need to wait, start a search with us today! If you want to find out a bit more about the journey first, you can find our train timetable below, tips on booking cheap tickets and our FAQs, including first and last train times.

Trains to Palermo Centrale from Frankfurt (Main)

It takes an average of 26h 2m to travel from Frankfurt (Main) to Palermo Centrale by train, over a distance of around 861 miles (1385 km). There are normally 16 trains per day travelling from Frankfurt (Main) to Palermo Centrale and tickets for this journey start from £140.03 when you book in advance.

First train

05:50

Last train

22:20

Departure stationFrankfurt (Main)
Arrival stationPalermo Centrale
Journey time

From 23h 4m

Distance

861 miles (1385 km)

Frequency

16 trains per day

Changes

2 changes

Price

From £140.03

Train and bus operators

Onebus

What do people frequently ask about the train journey from Frankfurt (Main) to Palermo Centrale?

Want to know more about your journey from Frankfurt (Main) to Palermo Centrale? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Frankfurt (Main) to Palermo Centrale?

You can get from Frankfurt (Main) to Palermo Centrale by train in 26 hours and 2 minutes on average, with the fastest journeys taking just 23 hours and 4 minutes. Check out our Journey Planner for more details.

How long does the train from Frankfurt (Main) to Palermo Centrale take?

The average journey time by train between Frankfurt (Main) and Palermo Centrale is 26 hours and 2 minutes, with around 16 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

How much does the train from Frankfurt (Main) to Palermo Centrale cost?

Train tickets from Frankfurt (Main) to Palermo Centrale can start from as little as £140.03 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending on the time of day, route and class you book.

What's the fastest journey time between Frankfurt (Main) and Palermo Centrale by train?

The fastest journey time by train from Frankfurt (Main) to Palermo Centrale is 23 hours and 4 minutes.

What are the train times from Frankfurt (Main) to Palermo Centrale?

Check out the next trains departing from Frankfurt (Main) to Palermo Centrale for Tuesday 12th May 2026. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
09:5009:5424h 4m, 6 changes
09:5010:5525h 5m, 4 changes
10:5009:5423h 4m, 7 changes
10:5010:5524h 5m, 5 changes
10:5714:2627h 29m, 4 changes
10:5715:5528h 58m, 2 changes
13:2016:3027h 10m, 6 changes
14:5718:0527h 8m, 5 changes
15:5020:5629h 6m, 8 changes
16:5020:5628h 6m, 9 changes

How do I find cheap train tickets from Frankfurt (Main) to Palermo Centrale?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Frankfurt (Main) to Palermo Centrale starts at £140.03§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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