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Trains from Frankfurt (Main) to Palermo Centrale

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  1. Home
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  3. Frankfurt (Main) to Palermo Centrale

Trains to Palermo Centrale from Frankfurt (Main)

Want to travel from Frankfurt (Main) to Palermo Centrale by train? Start your journey with us.

It takes an average of 28 hours 28 minutes to travel from Frankfurt (Main) to Palermo Centrale by train. You'll find on average 14 trains per day running on this route.

There aren't any direct services on this line, but it's still easy to travel to Palermo Centrale by train; you'll need to make 2 changes.

Generally, booking Advance train tickets works out cheaper.

See our Journey Planner for up-to-date times and prices.

Trains to Palermo Centrale from Frankfurt (Main)

First train

02:45

Last train

18:50

Departure stationFrankfurt (Main)
Arrival stationPalermo Centrale
Journey time

From 25h 11m

Distance

861 miles (1385 km)

Frequency

14 trains per day

Changes

2 changes

Train and bus operators

Onebus

What do people frequently ask about the train journey from Frankfurt (Main) to Palermo Centrale?

Want to know more about your journey from Frankfurt (Main) to Palermo Centrale? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I travel from Frankfurt (Main) to Palermo Centrale?

You can get from Frankfurt (Main) to Palermo Centrale by train in 28 hours and 28 minutes on average, with the fastest journeys taking just 25 hours and 11 minutes. Check out our Journey Planner for more details.

How long does the train from Frankfurt (Main) to Palermo Centrale take?

The average journey time by train between Frankfurt (Main) and Palermo Centrale is 28 hours and 28 minutes, with around 14 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

What's the fastest journey time between Frankfurt (Main) and Palermo Centrale by train?

The fastest journey time by train from Frankfurt (Main) to Palermo Centrale is 25 hours and 11 minutes.

Can you take a train directly from Frankfurt (Main) to Palermo Centrale?

No, there are no direct train services from Frankfurt (Main) to Palermo Centrale. Travelling from Frankfurt (Main) to Palermo Centrale by train will require a minimum of 2 changes.

What are the train times from Frankfurt (Main) to Palermo Centrale?

Check out the next trains departing from Frankfurt (Main) to Palermo Centrale for Tuesday 25th August 2026. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
05:5008:1326h 23m, 3 changes
05:5308:1326h 20m, 5 changes
07:0211:5128h 49m, 2 changes
09:5011:5126h 1m, 4 changes
10:5715:5528h 58m, 2 changes
13:2016:3427h 14m, 5 changes
13:2018:1028h 50m, 3 changes
14:5722:0131h 4m, 3 changes
15:5022:0130h 11m, 4 changes
16:5022:0129h 11m, 5 changes

How do I find cheap train tickets from Frankfurt (Main) to Palermo Centrale?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

2. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

3. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

4. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

5. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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