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Trains from Frankfurt (Main) Ost to Brussels Midi

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  1. Home
  2. Train times
  3. Frankfurt (Main) Ost to Brussels Midi

How to travel from Frankfurt (Main) Ost to Brussels Midi by train

Want to find out more about taking the train from Frankfurt (Main) Ost to Brussels Midi? Look no further.

There are around 15 trains per day running between Frankfurt (Main) Ost and Brussels Midi, which usually take 4 hours 36 minutes to complete the 199 miles (320 km) journey. It can take as little as 3 hours 40 minutes on the fastest services though, if you want to get there as quickly as possible. Although there aren't any direct services on this line, it's still easy to travel to Brussels Midi from Frankfurt (Main) Ost, you'll just need to make 1 change along the way.

You can save money on train tickets from Frankfurt (Main) Ost to Brussels Midi if you book in advance. Use our Journey Planner at the top of the page to compare ticket prices and get the cheapest fares.

Want to book your train tickets now? Just start a search with us today. If you want to find out more about the journey, read on for timetables (including first and last train times), FAQs and tips on how to book cheap train tickets.

Trains to Brussels Midi from Frankfurt (Main) Ost

First train

04:22

Last train

20:56

Departure stationFrankfurt (Main) Ost
Arrival stationBrussels Midi
Journey time

From 3h 40m

Distance

199 miles (320 km)

Frequency

15 trains per day

Changes

1 change

Train and bus operators

Flixbus

What do people frequently ask about the train journey from Frankfurt (Main) Ost to Brussels Midi?

Want to know more about your journey from Frankfurt (Main) Ost to Brussels Midi? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Brussels Midi from Frankfurt (Main) Ost?

To get to Brussels Midi from Frankfurt (Main) Ost, why not take the train? With 15 trains per day and an average journey time of 4 hours and 36 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Frankfurt (Main) Ost to Brussels Midi by train?

On average, it takes around 4 hours and 36 minutes to travel from Frankfurt (Main) Ost to Brussels Midi by train, although you can get there in 3 hours and 40 minutes on the fastest services. With 15 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How fast can trains travel from Frankfurt (Main) Ost to Brussels Midi?

The fastest time a train can travel the 199 miles (320 km) from Frankfurt (Main) Ost to Brussels Midi is 3 hours and 40 minutes.

Are there any direct trains from Frankfurt (Main) Ost to Brussels Midi?

There are no direct trains that run between Frankfurt (Main) Ost and Brussels Midi. You’ll need to make at least 1 change along the way.

What are the train times from Frankfurt (Main) Ost to Brussels Midi?

Check out the next trains departing from Frankfurt (Main) Ost to Brussels Midi for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
05:4909:353h 46m, 2 changes
06:5310:353h 42m, 1 change
08:5312:353h 42m, 1 change
09:5313:353h 42m, 2 changes
10:5314:353h 42m, 1 change
12:5316:353h 42m, 1 change
13:5417:353h 41m, 2 changes
14:5318:353h 42m, 1 change
15:5319:353h 42m, 2 changes
16:5520:353h 40m, 1 change

How do I find cheap train tickets from Frankfurt (Main) Ost to Brussels Midi?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Frankfurt (Main) Ost to Brussels Midi starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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