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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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Taking the train from Lyon Part-Dieu to Firenze Santa Maria Novella in 6 hours 34 minutes

Thinking about taking the train from Lyon Part-Dieu to Firenze Santa Maria Novella? We’ve got you covered.

It usually takes around 12 hours 10 minutes to travel the 342 miles (550 km) from Lyon Part-Dieu to Firenze Santa Maria Novella by train, although you can get there in as little as 6 hours 34 minutes on the fastest services. You’ll normally find around 18 trains per day running on this route. You’ll need to make 1 change along the way as there aren't any direct services on this line.

Train tickets from Lyon Part-Dieu to Firenze Santa Maria Novella start from £72.90 when you book in advance, which can be cheaper than buying them on the day. Start a search in our Journey Planner to check out the latest prices.

Keen to book your train tickets to Firenze Santa Maria Novella? No need to wait, start a search with us today! If you want to find out a bit more about the journey first, you can find our train timetable below, tips on booking cheap tickets and our FAQs, including first and last train times.

Trains to Firenze Santa Maria Novella from Lyon Part-Dieu

It takes an average of 12h 10m to travel from Lyon Part-Dieu to Firenze Santa Maria Novella by train, over a distance of around 342 miles (550 km). There are normally 18 trains per day travelling from Lyon Part-Dieu to Firenze Santa Maria Novella and tickets for this journey start from £72.90 when you book in advance.

First train

07:50

Last train

21:50

Departure stationLyon Part-Dieu
Arrival stationFirenze Santa Maria Novella
Journey time

From 6h 34m

Distance

342 miles (550 km)

Frequency

18 trains per day

Changes

1 change

Price

From £72.90

Train and bus operators

BlaBlaCar Bus, Flixbus, Itabus

What do people frequently ask about the train journey from Lyon Part-Dieu to Firenze Santa Maria Novella?

Want to know more about your journey from Lyon Part-Dieu to Firenze Santa Maria Novella? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Firenze Santa Maria Novella from Lyon Part-Dieu?

To get to Firenze Santa Maria Novella from Lyon Part-Dieu, why not take the train? With 18 trains per day and an average journey time of 12 hours and 10 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Lyon Part-Dieu to Firenze Santa Maria Novella by train?

On average, it takes around 12 hours and 10 minutes to travel from Lyon Part-Dieu to Firenze Santa Maria Novella by train, although you can get there in 6 hours and 34 minutes on the fastest services. With 18 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Lyon Part-Dieu to Firenze Santa Maria Novella?

The price of a train ticket from Lyon Part-Dieu to Firenze Santa Maria Novella can start from as little as £72.90, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Lyon Part-Dieu to Firenze Santa Maria Novella?

The fastest time a train can travel the 342 miles (550 km) from Lyon Part-Dieu to Firenze Santa Maria Novella is 6 hours and 34 minutes.

What are the train times from Lyon Part-Dieu to Firenze Santa Maria Novella?

Check out the next trains departing from Lyon Part-Dieu to Firenze Santa Maria Novella for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
08:3015:046h 34m, 1 change
09:3417:508h 16m, 2 changes
09:3819:049h 26m, 2 changes
09:4022:5013h 10m, 5 changes
16:2004:2812h 8m, 2 changes
16:2004:2812h 8m, 3 changes
16:2006:0413h 44m, 1 change
17:0207:0414h 2m, 5 changes
17:3809:5016h 12m, 4 changes
17:5609:5015h 54m, 5 changes

How do I find cheap train tickets from Lyon Part-Dieu to Firenze Santa Maria Novella?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Lyon Part-Dieu to Firenze Santa Maria Novella starts at £72.90§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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