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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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About the train journey from Firenze Santa Maria Novella to Lyon

Want to travel from Firenze Santa Maria Novella to Lyon by train? Start your journey with us.

The train from Firenze Santa Maria Novella to Lyon usually takes 13 hours 18 minutes on average to travel 343 miles (552 km), although the quickest services can take as little as 7 hours 12 minutes. You can expect to find 14 trains per day running on this popular route. As there aren’t any direct services running between Firenze Santa Maria Novella and Lyon, you’ll need to make 1 change on your way to Lyon.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Firenze Santa Maria Novella to Lyon in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save, as advance tickets start from £81.99.

Keep reading for more information about the train journey to Lyon, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Trains to Lyon from Firenze Santa Maria Novella

It takes an average of 13h 18m to travel from Firenze Santa Maria Novella to Lyon by train, over a distance of around 343 miles (552 km). There are normally 14 trains per day travelling from Firenze Santa Maria Novella to Lyon and tickets for this journey start from £81.99 when you book in advance.

First train

00:40

Last train

22:09

Departure stationFirenze Santa Maria Novella
Arrival stationLyon
Journey time

From 7h 12m

Distance

343 miles (552 km)

Frequency

14 trains per day

Changes

1 change

Price

From £81.99

Train and bus operators

BlaBlaCar Bus, Flixbus, Itabus

What do people frequently ask about the train journey from Firenze Santa Maria Novella to Lyon?

Want to know more about your journey from Firenze Santa Maria Novella to Lyon? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Lyon from Firenze Santa Maria Novella?

To get to Lyon from Firenze Santa Maria Novella, why not take the train? With 14 trains per day and an average journey time of 13 hours and 18 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Firenze Santa Maria Novella to Lyon by train?

On average, it takes around 13 hours and 18 minutes to travel from Firenze Santa Maria Novella to Lyon by train, although you can get there in 7 hours and 12 minutes on the fastest services. With 14 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Firenze Santa Maria Novella to Lyon?

The price of a train ticket from Firenze Santa Maria Novella to Lyon can start from as little as £81.99, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Firenze Santa Maria Novella to Lyon?

The fastest time a train can travel the 343 miles (552 km) from Firenze Santa Maria Novella to Lyon is 7 hours and 12 minutes.

What are the train times from Firenze Santa Maria Novella to Lyon?

Check out the next trains departing from Firenze Santa Maria Novella to Lyon for Tuesday 28th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
05:5516:5711h 2m, 4 changes
08:5517:108h 15m, 2 changes
11:5519:327h 37m, 1 change
12:2019:327h 12m, 2 changes
12:5521:108h 15m, 2 changes
15:5506:2214h 27m, 2 changes
16:1008:2216h 12m, 4 changes
16:5510:0117h 6m, 4 changes
17:2010:0116h 41m, 5 changes
20:5510:1513h 20m, 1 change

How do I find cheap train tickets from Firenze Santa Maria Novella to Lyon?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Firenze Santa Maria Novella to Lyon starts at £81.99§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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