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Travel from Karlstadt (Main) to Düsseldorf by train in 3 hours 12 minutes

If you want to know more about the journey from Karlstadt (Main) to Düsseldorf by train, look no further!

The average journey time from Karlstadt (Main) to Düsseldorf by train is 3 hours 50 minutes, although on the fastest services it can take just 3 hours 12 minutes. Around 36 trains per day travel the 157 miles (252 km) between these two destinations. You'll need to make 1 change along the way to Düsseldorf.

Book train tickets from Karlstadt (Main) to Düsseldorf in advance instead of buying them on the day and you'll snap up the cheapest fares. You can check prices from Karlstadt (Main) to Düsseldorf in our Journey Planner.

Ready to book? Start your search for cheap train tickets with us today. Keep reading for more information, including our timetable where you can view first and last train times, as well as tips on how to find cheap train tickets.

Trains to Düsseldorf from Karlstadt (Main)

First train

00:03

Last train

22:58

Departure stationKarlstadt (Main)
Arrival stationDüsseldorf
Journey time

From 3h 12m

Distance

157 miles (252 km)

Frequency

36 trains per day

Changes

1 change

What do people frequently ask about the train journey from Karlstadt (Main) to Düsseldorf?

Want to know more about your journey from Karlstadt (Main) to Düsseldorf? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Karlstadt (Main) to Düsseldorf?

You can travel from Karlstadt (Main) to Düsseldorf by train in about 3 hours and 50 minutes. With around 36 trains running each day, taking the train is easy. Find out more in our Journey Planner.

How long is the train journey from Karlstadt (Main) to Düsseldorf?

On average, the train journey from Karlstadt (Main) to Düsseldorf takes around 3 hours and 50 minutes, with 36 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

What is the fastest train from Karlstadt (Main) to Düsseldorf?

The fastest trains from Karlstadt (Main) to Düsseldorf can cover the distance of 157 miles (252 km) in as little as 3 hours and 12 minutes.

Is there a direct train from Karlstadt (Main) to Düsseldorf?

No, you can’t travel from Karlstadt (Main) to Düsseldorf on a direct train, you’ll need to make at least 1 change during the journey.

What are the train times from Karlstadt (Main) to Düsseldorf?

Check out the next trains departing from Karlstadt (Main) to Düsseldorf for Tuesday 14th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
09:5513:323h 37m, 3 changes
10:0013:363h 36m, 1 change
10:5514:323h 37m, 2 changes
11:0014:363h 36m, 1 change
11:5515:353h 40m, 3 changes
12:0015:383h 38m, 1 change
12:5516:313h 36m, 3 changes
13:1016:363h 26m, 1 change
13:5417:323h 38m, 3 changes
14:2217:363h 14m, 1 change

How do I find cheap train tickets from Karlstadt (Main) to Düsseldorf?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Karlstadt (Main) to Düsseldorf starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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