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How to travel from Madrid to Brussels Central by train

Want to find out more about taking the train from Madrid to Brussels Central? Look no further.

There are around 7 trains per day running between Madrid and Brussels Central, which usually take 20 hours 13 minutes to complete the 818 miles (1316 km) journey. It can take as little as 12 hours 44 minutes on the fastest services though, if you want to get there as quickly as possible. Although there aren't any direct services on this line, it's still easy to travel to Brussels Central from Madrid, you'll just need to make 3 changes along the way.

You can save money on train tickets from Madrid to Brussels Central if you book in advance. Use our Journey Planner at the top of the page to compare ticket prices and get the cheapest fares.

Want to book your train tickets now? Just start a search with us today. If you want to find out more about the journey, read on for timetables (including first and last train times), FAQs and tips on how to book cheap train tickets.

Trains to Brussels Central from Madrid

First train

06:16

Last train

21:07

Departure stationMadrid
Arrival stationBrussels Central
Journey time

From 12h 44m

Distance

818 miles (1316 km)

Frequency

7 trains per day

Changes

3 changes

Train and bus operators

Flixbus, iryo

What do people frequently ask about the train journey from Madrid to Brussels Central?

Want to know more about your journey from Madrid to Brussels Central? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you get to Brussels Central from Madrid?

To travel to Brussels Central from Madrid, you can take the train - on average, the journey takes around 20 hours and 13 minutes, though the fastest trains can take 12 hours and 44 minutes. Use our Journey Planner to get more information.

How long is the train ride from Madrid to Brussels Central?

Trains from Madrid to Brussels Central take an average of 20 hours and 13 minutes, although on the fastest services it can take just 12 hours and 44 minutes. You'll usually find 7 trains per day on this route, so use our Journey Planner to check specific dates as times may vary.

Can I get a high-speed train from Madrid to Brussels Central?

Yes, you can get a high-speed train from Madrid to Brussels Central in as little as 12 hours and 44 minutes on the fastest services. High-speed trains from iryo offer a range of classes and onboard services - take a look to see what suits you best!

What is the quickest journey time between Madrid and Brussels Central by train?

The quickest journey time between Madrid and Brussels Central by train is 12 hours and 44 minutes.

What are the train times from Madrid to Brussels Central?

Check out the next trains departing from Madrid to Brussels Central for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
05:1618:0012h 44m, 3 changes
06:2706:4724h 20m, 6 changes
06:5706:4723h 50m, 7 changes
11:5706:5518h 58m, 3 changes
12:1808:2620h 8m, 3 changes
20:0717:1121h 4m, 3 changes

iryo trains from Madrid to Brussels Central

You can travel from Madrid to Brussels Central on iryo trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Operating since the end of 2022, iryo is a new high-speed train company in Spain. It’s a consortium between the Spanish airline Air Norstrum and the train company Trenitalia, one of the greatest leaders in European rail transport. The first private Spanish high-speed company to operate, iryo runs high-speed services on the Madrid – Zaragoza – Barcelona route and connects Madrid – Cuenca – Valencia/Alicante and Madrid – Cordoba – Seville/Malaga. They are doing this all with a fleet of ETR1000 model trains that offer the highest level of comfort in Spain, with a combination of advanced propulsion and highest quality onboard services, including WiFi connection and catering service. 98% of the parts of the trains are 100% recyclable, making this trip sustainable as well!

What iryo classes are there from Madrid to Brussels Central?

Compare the different travel classes offered by iryo when travelling from Madrid to Brussels Central.

What are the onboard services on iryo?

Discover more about the onboard services offered on trains from Madrid to Brussels Central.

LuggageLuggageWhat luggage limits are there?

Iryo's luggage policy varies by class. With an Inicial ticket, you can take one carry-on bag measuring 36 x 27 x 15 cm and one cabin suitcase measuring 55 x 35 x 25 cm. With a Singular (and Singular Only YOU) ticket, you can also take one large suitcase measuring 80 x 55 x 35 cm. The Infinita Bistró fare includes all of the above and also allows travel with one pet inside a carrier.

RestaurantRestaurantWhat food and drink is available?

iryo offers different menus with high-quality products in all classes. You can buy your favourite meal from their onboard restaurant/bar carriage, which is usually near coach 2.

If you’re travelling in the Infinita Bistró Class, you can enjoy the Infinita Bistró food service – your meal will be served straight to your seat. Please note that you’ll need to book your meal at least 24 hours in advance.

WiFiWiFiWhat onboard entertainment is available?

You can enjoy free WiFi in all classes on iryo trains, as well as an onboard entertainment platform providing a wide selection of movies, TV series, live news and Spotify.

ChildPassengerChildPassengerWhat facilities are there for travel with children?

Children aged 0-3 travel for free on all iryo trains. Children aged 4-13 get a discounted ticket while those aged 14-18 need to pay the full price. Please note that children aged under 18 need to be accompanied by their parents or legal guardians.

ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?

You can take your bike on board iryo trains for free if it’s folded and does not exceed 90 x 120 x 40cm. Also, your bike must travel without the pedals and with the handlebar rotated 90 degrees.

PetPetCan I bring pets on board?

iryo allows pets that do not exceed 10kg in weight, as long as they travel inside a carrier with a maximum size of 60 x 35 x 35cm. You'll need to buy a ticket for your pet in advance. In addition, guide dogs can travel at no additional cost.

WheelchairWheelchairWhat special assistance is available?

There are seats for people with reduced mobility on iryo trains. Step-free access is also available both when boarding and when getting off the train.

How do I find cheap train tickets from Madrid to Brussels Central?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Madrid to Brussels Central starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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