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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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Travelling from Karlsruhe Hbf to Firenze Santa Maria Novella by train

Looking to travel from Karlsruhe Hbf to Firenze Santa Maria Novella by train? You've come to the right place!

On average, it takes around 10 hours 13 minutes to travel from Karlsruhe Hbf to Firenze Santa Maria Novella by train, the fastest services can get you there in as little as 8 hours 28 minutes though. You'll usually find 26 trains per day running along the 385 miles (620 km) route between these two destinations. You’ll need to make 1 change during the journey to Firenze Santa Maria Novella, as there currently aren't any direct services on this route.

Plan your trip ahead of time and book early if you want to snap up the cheapest fares. Tickets from Karlsruhe Hbf to Firenze Santa Maria Novella start from £117.34 when you book in advance, so use our Journey Planner to view the latest prices.

If you’re feeling ready to book, start looking for cheap train tickets with us today. Keep reading for more information on the journey to Firenze Santa Maria Novella by train, including our timetable where you can view first and last train times.

Trains to Firenze Santa Maria Novella from Karlsruhe Hbf

It takes an average of 10h 13m to travel from Karlsruhe Hbf to Firenze Santa Maria Novella by train, over a distance of around 385 miles (620 km). There are normally 26 trains per day travelling from Karlsruhe Hbf to Firenze Santa Maria Novella and tickets for this journey start from £117.34 when you book in advance.

First train

04:03

Last train

23:13

Departure stationKarlsruhe Hbf
Arrival stationFirenze Santa Maria Novella
Journey time

From 8h 28m

Distance

385 miles (620 km)

Frequency

26 trains per day

Changes

1 change

Price

From £117.34

Train and bus operators

Flixbus

What do people frequently ask about the train journey from Karlsruhe Hbf to Firenze Santa Maria Novella?

Want to know more about your journey from Karlsruhe Hbf to Firenze Santa Maria Novella? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Firenze Santa Maria Novella from Karlsruhe Hbf?

To get to Firenze Santa Maria Novella from Karlsruhe Hbf, why not take the train? With 26 trains per day and an average journey time of 10 hours and 13 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Karlsruhe Hbf to Firenze Santa Maria Novella by train?

On average, it takes around 10 hours and 13 minutes to travel from Karlsruhe Hbf to Firenze Santa Maria Novella by train, although you can get there in 8 hours and 28 minutes on the fastest services. With 26 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Karlsruhe Hbf to Firenze Santa Maria Novella?

The price of a train ticket from Karlsruhe Hbf to Firenze Santa Maria Novella can start from as little as £117.34, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Karlsruhe Hbf to Firenze Santa Maria Novella?

The fastest time a train can travel the 385 miles (620 km) from Karlsruhe Hbf to Firenze Santa Maria Novella is 8 hours and 28 minutes.

What are the train times from Karlsruhe Hbf to Firenze Santa Maria Novella?

Check out the next trains departing from Karlsruhe Hbf to Firenze Santa Maria Novella for Tuesday 21st October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
06:5916:049h 5m, 3 changes
07:0616:048h 58m, 4 changes
08:1116:398h 28m, 4 changes
08:1116:508h 39m, 3 changes
08:1117:048h 53m, 1 change
08:5917:508h 51m, 4 changes
08:5918:049h 5m, 2 changes
10:0019:049h 4m, 3 changes
10:5919:508h 51m, 4 changes
10:5920:049h 5m, 3 changes

How do I find cheap train tickets from Karlsruhe Hbf to Firenze Santa Maria Novella?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Karlsruhe Hbf to Firenze Santa Maria Novella starts at £117.34§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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