Festive French seats are live for travel between Dec 14 to early Jan* – book in advance to save! Ho, ho, gooo…

Skip to contentTrainline homepage
RailcardsBusiness

No tickets in your basket.

Why not plan a trip?

My Bookings
Loading...
Loading...

Trains from Siena to Lyon Part-Dieu

Booking.com

ExternalLinkExternalLink

Open Booking.com in a new tab with places to stay on your trip

SNCF
Trenitalia

Compare prices from over 270 rail and coach companies in Europe

Icon of trainline-phone-tickets.svg

Buy your tickets with us and easily find them on your phone

Icon of trainline-safe-payments.svg

Safely pay with PayPal, Visa and all international payment cards

What customers say about Trainline

Read real reviews from real users

Trustpilot
  1. Home
  2. Train times
  3. Siena to Lyon Part-Dieu

Take the train from Siena to Lyon Part-Dieu in 8 hours 14 minutes

If you want to travel from Siena to Lyon Part-Dieu by train, you've come to the right place.

You can expect the journey from Siena to Lyon Part-Dieu by train to take around 14 hours 51 minutes. If you want to get there as quickly as possible, it can take as little as 8 hours 14 minutes on the fastest services. You’ll usually find around 15 trains per day running on this route, which spans 360 miles (579 km). You’ll have to make 2 changes along the way on your journey to Lyon Part-Dieu.

You can save money on train tickets from Siena to Lyon Part-Dieu if you book in Use our Journey Planner at the top of the page to search for cheap ticket prices – we'll show you how much you can save on train tickets from Siena to Lyon Part-Dieu if you book in advance.. Use our Journey Planner at the top of the page to compare ticket prices and get the cheapest fares.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Trains to Lyon Part-Dieu from Siena

First train

07:02

Last train

21:40

Departure stationSiena
Arrival stationLyon Part-Dieu
Journey time

From 8h 14m

Distance

360 miles (579 km)

Frequency

15 trains per day

Changes

2 changes

Train and bus operators

Flixbus

What do people frequently ask about the train journey from Siena to Lyon Part-Dieu?

Want to know more about your journey from Siena to Lyon Part-Dieu? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Lyon Part-Dieu from Siena?

To get to Lyon Part-Dieu from Siena, why not take the train? With 15 trains per day and an average journey time of 14 hours and 51 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Siena to Lyon Part-Dieu by train?

On average, it takes around 14 hours and 51 minutes to travel from Siena to Lyon Part-Dieu by train, although you can get there in 8 hours and 14 minutes on the fastest services. With 15 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How fast can trains travel from Siena to Lyon Part-Dieu?

The fastest time a train can travel the 360 miles (579 km) from Siena to Lyon Part-Dieu is 8 hours and 14 minutes.

Are there any direct trains from Siena to Lyon Part-Dieu?

There are no direct trains that run between Siena and Lyon Part-Dieu. You’ll need to make at least 2 changes along the way.

What are the train times from Siena to Lyon Part-Dieu?

Check out the next trains departing from Siena to Lyon Part-Dieu for Tuesday 7th October 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
10:1819:329h 14m, 3 changes
10:4521:1010h 25m, 4 changes
11:1819:328h 14m, 2 changes
13:1806:2217h 4m, 3 changes
13:4106:2216h 41m, 4 changes
14:1808:2218h 4m, 5 changes
15:1809:4418h 26m, 9 changes
15:1810:0118h 43m, 6 changes
18:1810:1515h 57m, 2 changes
18:4110:1515h 34m, 3 changes

How do I find cheap train tickets from Siena to Lyon Part-Dieu?

If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

1. Book in advance

The price of train tickets from Siena to Lyon Part-Dieu starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

2. Be flexible with your travel times

If you can, consider travelling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as many train companies increase their ticket prices during these commuter times.

3. Buy a rail pass

If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Interrail Passes that are valid for travel within one country or multiple countries across Europe.

4. Choose a slower or connecting train

On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

5. Look out for train ticket sales and discounts

Many train companies in Europe will often run sales on tickets throughout the year or offer discounts to senior/youth/group travellers, so keep an eye out!

6. Take a night train

Save on accommodation and use the night to travel by sleeper train to your next destination.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

Europe’s leading train and coach app

We help customers across Europe make more than 172,000 smarter journeys every day.

Get a link