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Trains from Pisa Centrale to Frankfurt (Main) Hbf

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    3. Pisa Centrale to Frankfurt (Main) Hbf

    About the train journey from Pisa Centrale to Frankfurt (Main) Hbf

    Want to travel from Pisa Centrale to Frankfurt (Main) Hbf by train? Start your journey with us.

    The train from Pisa Centrale to Frankfurt (Main) Hbf usually takes 13 hours 43 minutes on average to travel 724 km, although the quickest services can take as little as 10 hours 43 minutes. You can expect to find 32 trains per day running on this popular route. As there aren't any direct services running between Pisa Centrale and Frankfurt (Main) Hbf, you'll need to make 1 change on your way to Frankfurt (Main) Hbf.

    To help you get the best train deals, we'll highlight the cheapest train ticket prices from Pisa Centrale to Frankfurt (Main) Hbf in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save!

    Keep reading for more information about the train journey to Frankfurt (Main) Hbf, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you're ready to book, just start a search for tickets with us today.

    Pisa Centrale to Frankfurt (Main) Hbf by train

    First train

    3:26 am

    Last train

    10:53 pm

    Departure station

    Pisa Centrale

    Arrival station

    Frankfurt (Main) Hbf

    Journey time

    From 10h 43m

    Distance

    450 miles (724 km)

    Frequency

    32 trains per day

    Changes

    1 change

    Train and bus operators

    Flixbus

    What do people frequently ask about the train journey from Pisa Centrale to Frankfurt (Main) Hbf?

    Want to know more about your journey from Pisa Centrale to Frankfurt (Main) Hbf? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

    How do you travel to Frankfurt (Main) Hbf from Pisa Centrale?

    To get to Frankfurt (Main) Hbf from Pisa Centrale, why not take the train? With 32 trains per day and an average journey time of 13 hours and 43 minutes, taking the train is a great way to travel. See our Journey Planner for up-to-date times and prices.

    How long does it take to get from Pisa Centrale to Frankfurt (Main) Hbf by train?

    On average it takes around 13 hours and 43 minutes to travel from Pisa Centrale to Frankfurt (Main) Hbf by train, although you can get there in 10 hours and 43 minutes on the fastest services. With 32 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

    How fast can trains travel from Pisa Centrale to Frankfurt (Main) Hbf?

    The fastest time a train can travel the 450 miles (724 km) from Pisa Centrale to Frankfurt (Main) Hbf is 10 hours and 43 minutes.

    Are there any direct trains from Pisa Centrale to Frankfurt (Main) Hbf?

    There are no direct trains that run between Pisa Centrale and Frankfurt (Main) Hbf. You’ll need to make around 1 change along the way.

    What are the train times from Pisa Centrale to Frankfurt (Main) Hbf?

    Check out the next trains departing from Pisa Centrale to Frankfurt (Main) Hbf for Tuesday Sep 30th 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
    DepartsArrivesDuration
    8:32 am8:08 pm11h 36m, 3 changes
    9:32 am10:04 pm12h 32m, 5 changes
    10:09 am10:04 pm11h 55m, 6 changes
    10:30 am10:08 pm11h 38m, 3 changes
    10:42 am11:43 pm13h 1m, 4 changes
    11:32 am11:43 pm12h 11m, 5 changes
    12:32 pm1:40 am13h 8m, 4 changes
    12:39 pm3:08 am14h 29m, 3 changes
    1:32 pm3:08 am13h 36m, 4 changes
    1:56 pm8:52 am18h 56m, 2 changes

    How do I find cheap train tickets from Pisa Centrale to Frankfurt (Main) Hbf?

    If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

    1. Book in advance

    The price of train tickets from Pisa Centrale to Frankfurt (Main) Hbf starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

    2. Be flexible with your travel times

    If you can, consider traveling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as lots of trains companies increase their ticket prices during these commuter times.

    3. Buy a rail pass

    If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Eurail Passes that are valid for travel in one country or multiple countries across Europe.

    4. Choose a slower or connecting train

    On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

    5. Look out for train ticket sales and deals

    Many train companies in Europe will often run sales and offers on tickets throughout the year, so keep an eye out!

    For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

    §Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

    * Based on European average monthly visitors to Trainline’s app and website from 1.1.2023 to 10.31.2023 vs other independent retailers.

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