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Traveling from Pisa to Madrid by train

Looking to travel from Pisa to Madrid by train? You've come to the right place!

On average, it takes around 25 hours 51 minutes to travel from Pisa to Madrid by train, the fastest services can get you there in as little as 22 hours 22 minutes though. You'll usually find 6 trains per day running along the 1219 km route between these two destinations. You'll need to make 5 changes during the journey to Madrid, as there currently aren't any direct services on this route. You'll be traveling with TGV, AVE or Avlo on your way to Madrid, as these are the main rail operators on this route.

Plan your trip ahead of time and book early if you want to snap up the cheapest fares. Tickets from Pisa to Madrid start from $322.64 when you book in advance, so start a search in our Journey Planner to view the latest prices.

If you're feeling ready to book, start looking for cheap train tickets with us today. Keep reading for more information on the journey to Madrid by train, including our train schedule where you can view first and last train times.

Pisa to Madrid by train

It takes an average of 25h 51m to travel from Pisa to Madrid by train, over a distance of around 757 miles (1219 km). There are normally 6 trains per day traveling from Pisa to Madrid and tickets for this journey start from $322.64 when you book in advance.

First train


Last train


Departure station


Arrival station


Journey time

22h 22m


1219 miles (757 km)


6 trains per day


5 changes


From $322.64

Train and bus operators

OUIGO, Trenitalia, SNCF, Renfe-SNCF, Renfe, ALSA

Pisa to Madrid train times

Check out the next trains departing from Pisa to Madrid for Tuesday Feb 14th 2023. For the full train timetable/schedule, or to search for a later time or date, click here.
05:42 07:50 26h 8m, 6 changes
10:30 14:45 28h 15m, 7 changes
12:02 16:55 28h 53m, 8 changes
18:03 18:45 24h 42m, 5 changes
18:56 18:45 23h 49m, 6 changes
20:23 18:45 22h 22m, 7 changes

Trenitalia, Intercity, OUIGO and SNCF trains from Pisa to Madrid

You can travel from Pisa to Madrid on Trenitalia, Intercity, OUIGO and SNCF trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

PhotoChris0693, under licence CC3.0

Trenitalia's Intercity trains run on standard lines outside the high-speed network, offering more than 90 trains a day that guarantee long and medium distance connections, ensuring wide coverage of the rail network. All Intercity trains are modern and comfortable with plenty of seats, retractable tables, power sockets, air conditioning, courtesy lights and plenty of luggage space. Intercity Night trains allow you to travel overnight in cabins with beds, berths or seating.

PhotoCramos, under licence CC BY-SA 4.0

OUIGO is the low-cost, high-speed train service operated by the French national train company SNCF. Despite having only one class on board, OUIGO trains offer the same comfort as Second Class seats on TGV trains, although OUIGO tickets are only available to purchase online. To make your journey as smooth as possible, arrive at least 30 minutes before departure and bear in mind that there's an additional fee for bringing a suitcase with you, having a seat with power sockets and travelling with a stroller/buggy.

PhotoCtruongngoc, under licence CC BY-SA 3.0

SNCF is the national train operator of France. It operates all domestic trains and routes across France, as well as international services to Spain and Germany. There are three different types of domestic trains that operate under the SNCF banner – TGV (high-speed, full-service trains that connect the major cities in France), Intercités (usually a more frequent stopping service, but with all the amenities), and TER (regional train services with basic onboard facilities).

Cheap train tickets from Pisa to Madrid

The price of train tickets from Pisa to Madrid starts at $322.64 one-way for a Standard Class ticket if you book in advance. Booking on the day is usually more expensive and costs can vary depending on the time of day, route or class.

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Pisa to Madrid by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

FAQs for Pisa to Madrid

Want to know more about your journey from Pisa to Madrid? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How long does the train from Pisa to Madrid take?

The average journey time by train between Pisa and Madrid is 25 hours and 51 minutes, with around 6 trains per day. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

What's the fastest journey time between Pisa and Madrid by train?

The fastest journey time by train from Pisa to Madrid is 22 hours and 22 minutes.

How much does the train from Pisa to Madrid cost?

Train tickets from Pisa to Madrid can start from as little as $322.64 when you book in advance and are usually more expensive when purchased on the day. Prices can also vary depending the time of day, route and class you book.

Is there a direct train from Pisa to Madrid?

No, there are no direct train services from Pisa to Madrid. Travelling from Pisa to Madrid by train will require a minimum of 5 changes.

What time does the first train from Pisa to Madrid leave?

The first train from Pisa to Madrid leaves at 06:42. Times and services may vary during weekends and holidays.

What time does the last train from Pisa to Madrid leave?

The last train from Pisa to Madrid leaves at 21:23. Trains that depart in the early morning hours or very late evening may be sleeper services, time and services may also vary during weekends and holidays.

What's the distance between Pisa and Madrid by train?

Trains travelling from Pisa to Madrid cover a distance of around 757 miles (1219 km) during the journey.

Looking for more information?

If you’re looking for the return train journey, check out trains from Madrid to Pisa.
The information provided is calculated based on scheduled train services for Pisa to Madrid for a typical week day using timetable data for 02/14/2023. On weekends, holidays or other exceptional times, fewer services may be available. The fare range provided has been found by our customers on Trainline on 08/28/2022 for travel on 08/28/2022 and for adult tickets in economy, discount cards and coach journeys excluded.

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