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    Take the train from Milan to Palermo Centrale in 13 hours 20 minutes

    If you want to travel from Milan to Palermo Centrale by train, you've come to the right place.

    You can expect the journey from Milan to Palermo Centrale by train to take around 17 hours 6 minutes. If you want to get there as quickly as possible, it can take as little as 13 hours 20 minutes on the fastest services. You'll usually find around 18 trains per day running on this route, which spans 888 km. There's no need for any changes along the way, as there are direct trains available to Palermo Centrale. Trenitalia trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Palermo Centrale.

    Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from Milan to Palermo Centrale start from $73.61 when you book in advance.

    If you want to know more about the journey, keep reading for train schedules, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

    Milan to Palermo Centrale by train

    It takes an average of 17h 6m to travel from Milan to Palermo Centrale by train, over a distance of around 552 miles (888 km). There are normally 18 trains per day traveling from Milan to Palermo Centrale and tickets for this journey start from $73.61 when you book in advance.

    First train

    5:30 am

    Last train

    9:35 pm

    Departure station

    Milan

    Arrival station

    Palermo Centrale

    Journey time

    From 13h 20m

    Distance

    552 miles (888 km)

    Frequency

    18 trains per day

    Changes

    Direct trains available

    Price

    From $73.61

    Train and bus operators

    Autoservizi Salemi, Flixbus, Treni Turistici Italiani, Trenitalia

    What do people frequently ask about the train journey from Milan to Palermo Centrale?

    Want to know more about your journey from Milan to Palermo Centrale? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

    How do I get from Milan to Palermo Centrale?

    You can travel from Milan to Palermo Centrale by train in about 17 hours and 6 minutes. With around 18 trains available on this route each day, taking the train is easy. Find out more about times, tickets and prices using our Journey Planner.

    How long is the train trip from Milan to Palermo Centrale?

    On average, the train trip from Milan to Palermo Centrale takes around 17 hours and 6 minutes, with 18 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

    How much is the train from Milan to Palermo Centrale?

    Train tickets from Milan to Palermo Centrale start from as little as $73.61, depending on the time of booking, class of service and type of train. Booking in advance often results in better prices.

    What is the fastest train from Milan to Palermo Centrale?

    The fastest trains from Milan to Palermo Centrale can cover the distance of 552 miles (888 km) in as little as 13 hours and 20 minutes.

    What are the train times from Milan to Palermo Centrale?

    Check out the next trains departing from Milan to Palermo Centrale for Tuesday Sep 30th 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
    DepartsArrivesDuration
    8:20 am9:55 pm13h 35m, 2 changes
    8:35 am9:55 pm13h 20m, 3 changes
    1:30 pm6:52 am17h 22m, 2 changes
    5:00 pm8:22 am15h 22m, 1 change
    5:30 pm8:22 am14h 52m, 2 changes
    6:35 pm12:32 pm17h 57m, 2 changes
    6:35 pm1:25 pm18h 50m, 1 change
    6:35 pm10:57 am16h 22m, 2 changes
    7:10 pm3:55 pm20h 45m, direct
    7:10 pm3:55 pm20h 45m, 1 change

    Trenitalia trains from Milan to Palermo Centrale

    You can travel from Milan to Palermo Centrale on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

    Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

    What Intercity Notte (night trains) classes are there from Milan to Palermo Centrale?

    Compare the different travel classes offered by Intercity Notte (night trains) when traveling from Milan to Palermo Centrale.

    What are the onboard services on Intercity Notte (night trains)?

    Discover more about the onboard services offered on trains from Milan to Palermo Centrale.

    LuggageLuggageWhat baggage limits are there?
    • You can take your bags on board Trenitalia's Intercity Notte trains free of charge.
    • In most cases, there are no baggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your baggage is compatible with the space available on board.
    RestaurantRestaurantWhat food and drink is available?

    A minibar trolley service is available on all Intercity Notte trains – you can choose from a wide range of snacks and drinks. Vegan, gluten-free and lactose-free options are available too.

    WiFiWiFiWhat onboard entertainment is available?

    Unfortunately, free WiFi is not available on Intercity Notte trains.

    ChildPassengerChildPassengerWhat facilities are there for travel with children?
    • Kids under 4 can travel for free if a seat is not assigned to them. If they do have a seat, they can get 50% off Base tickets (standard fare).
    • Children aged 4-14 also get 50% off, or 30% off if they’re traveling in the Comfort couchette or Deluxe cabin Relax.
    ModeOfTransportBikeModeOfTransportBikeCan I bring a bike on board?
    • You can take your folding bike with you if it’s stored in one of the dedicated luggage spaces.
    • If you have a traditional bike, you’ll need to disassemble it and place it in a bag that is not larger than 80 x 110 x 45cm (31.4 x 43.3 x 17.7 inches).
    PetPetCan I bring pets on board?
    • Small pets are allowed on board free of charge, if they’re placed in a carrier or cage of max dimensions of 70 x 30 x 50cm (27.5 x 11.8 x 19.6 inches). You’ll need to buy a ticket for the whole compartment.
    • Bigger dogs are allowed on board if they have a ticket – it’s usually 50% off the Base ticket (standard fare).
    WheelchairWheelchairWhat special assistance is available?

    Intercity Notte trains have a car with designated spaces for 2 passengers with a wheelchair and 2 companions. You’ll find a wheelchair symbol outside the car.

    InfoInfoWhat else do I need to know?

    Depending on the class you’ll be traveling in, you’ll get to enjoy additional perks, including a wake-up service, breakfast, bedding and more.

    How do I find cheap train tickets from Milan to Palermo Centrale?

    If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

    1. Book in advance

    The price of train tickets from Milan to Palermo Centrale starts at $73.61§ one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

    2. Be flexible with your travel times

    If you can, consider traveling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as lots of trains companies increase their ticket prices during these commuter times.

    3. Buy a rail pass

    If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Eurail Passes that are valid for travel in one country or multiple countries across Europe.

    4. Choose a slower or connecting train

    On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

    5. Look out for train ticket sales and deals

    Many train companies in Europe will often run sales and offers on tickets throughout the year, so keep an eye out!

    For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

    §Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

    * Based on European average monthly visitors to Trainline’s app and website from 1.1.2023 to 10.31.2023 vs other independent retailers.

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