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    Take the train from Mainz Hbf to Prague in 7 hours 50 minutes

    If you want to travel from Mainz Hbf to Prague by train, you've come to the right place.

    You can expect the journey from Mainz Hbf to Prague by train to take around 9 hours 11 minutes. If you want to get there as quickly as possible, it can take as little as 7 hours 50 minutes on the fastest services. You'll usually find around 35 trains per day running on this route, which spans 442 km. You'll have to make 1 change along the way on your journey to Prague. ÖBB trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Prague.

    Use our Journey Planner at the top of the page to search for cheap ticket prices – we'll show you how much you can save on train tickets from Mainz Hbf to Prague if you book in advance.

    If you want to know more about the journey, keep reading for train schedules, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

    Mainz Hbf to Prague by train

    First train

    2:02 am

    Last train

    11:32 pm

    Departure station

    Mainz Hbf

    Arrival station

    Prague

    Journey time

    From 7h 50m

    Distance

    275 miles (442 km)

    Frequency

    35 trains per day

    Changes

    1 change

    Train and bus operators

    Flixbus, ÖBB

    What do people frequently ask about the train journey from Mainz Hbf to Prague?

    Want to know more about your journey from Mainz Hbf to Prague? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

    How do I travel from Mainz Hbf to Prague?

    You can get from Mainz Hbf to Prague in 9 hours and 11 minutes on average, with the fastest trains taking just 7 hours and 50 minutes. Check out our Journey Planner for more details on times, tickets and prices.

    How long does the train from Mainz Hbf to Prague take?

    The average journey time by train between Mainz Hbf and Prague is 9 hours and 11 minutes, with around 35 trains per day running on this route. The journey time may be longer on weekends and holidays, so use our Journey Planner on this page to search for a specific travel date.

    What's the fastest journey time between Mainz Hbf and Prague by train?

    The fastest journey time by train from Mainz Hbf to Prague is 7 hours and 50 minutes.

    Can you take a train directly from Mainz Hbf to Prague?

    No, there are no direct train services from Mainz Hbf to Prague. Travelling from Mainz Hbf to Prague by train will require a minimum of 1 change.

    What are the train times from Mainz Hbf to Prague?

    Check out the next trains departing from Mainz Hbf to Prague for Tuesday Dec 16th 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
    DepartsArrivesDuration
    8:13 am4:15 pm8h 2m, 4 changes
    9:02 am5:21 pm8h 19m, 3 changes
    9:02 am6:15 pm9h 13m, 2 changes
    10:10 am6:15 pm8h 5m, 3 changes
    10:10 am7:21 pm9h 11m, 2 changes
    10:13 am6:15 pm8h 2m, 4 changes
    11:02 am7:21 pm8h 19m, 3 changes
    11:02 am8:15 pm9h 13m, 2 changes
    12:10 pm8:15 pm8h 5m, 3 changes
    12:10 pm9:11 pm9h 1m, 2 changes

    ÖBB trains from Mainz Hbf to Prague

    You can travel from Mainz Hbf to Prague on ÖBB trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

    ÖBB is the major railway company for Austria, subdivided into several subsidiaries, responsible for certain areas of transport, such as long distance and local transport, the operation of postal buses and the transport of goods. Railjet is ÖBB's high-speed train, which travels at speeds of up to 143 mph (230 km/h) and connects the main Austrian cities with Germany, Hungary, Switzerland, the Czech Republic and Italy.

    How do I find cheap train tickets from Mainz Hbf to Prague?

    If you’re planning a trip to Europe soon, our Trainline team of experts have put together some tips to help you find cheap tickets. Booking on the day in Europe is usually more expensive and costs can vary depending on the time of day, route or travel class.

    1. Book in advance

    The price of train tickets from Mainz Hbf to Prague starts at § one-way for a Standard Class ticket if you book in advance. Most train companies across Europe release their tickets around three to six months ahead of time, so if you know the dates you want to travel, you may be able to find cheaper tickets.

    2. Be flexible with your travel times

    If you can, consider traveling outside of 'peak hours' (generally between 06:00 - 10:00 and 15:00 - 19:00 on weekdays) as lots of trains companies increase their ticket prices during these commuter times.

    3. Buy a rail pass

    If you're visiting multiple locations on your trip, buying a rail pass can be cheaper than buying individual tickets. We're official retailers of Eurail Passes that are valid for travel in one country or multiple countries across Europe.

    4. Choose a slower or connecting train

    On some busier routes, you might have the option to take a slower or connecting train. It may take longer than some high-speed or direct services, but if you have some extra time on your hands, you might find a cheaper fare.

    5. Look out for train ticket sales and deals

    Many train companies in Europe will often run sales and offers on tickets throughout the year, so keep an eye out!

    For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

    §Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

    * Based on European average monthly visitors to Trainline’s app and website from 1.1.2023 to 10.31.2023 vs other independent retailers.

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